Natural history of Chiari type I malformation in children

Luca Massimi, Massimo Caldarelli, Paolo Frassanito, Concezio Di Rocco

Research output: Contribution to journalArticlepeer-review

Abstract

The decision on whether or not to operate children with Chiari type I malformation (CIM) is difficult and controversial, because of the lack of information about the natural evolution of such a disease. Herein, we report on the evolution of 16 asymptomatic children with incidentally diagnosed CIM (mean age: 6.7 years; mean follow-up: 5.8 years). No patients required suboccipital decompression. Thirteen children remained asymptomatic, with stable or improved radiological picture (worsening in 2 cases). Three cases showed appearance of symptoms: one did not require any treatment; the remaining two underwent endoscopic third ventriculostomy because of hydrocephalus, which is a possible consequence of CIM. This analysis shows a favorable natural outcome of CIM in children, thus suggesting a conservative management in asymptomatic cases. However, multicentric studies are required to validate this data.

Original languageEnglish
Pages (from-to)1-3
Number of pages3
JournalNeurological Sciences
DOIs
Publication statusAccepted/In press - 2011

Keywords

  • Asymptomatic patients
  • Cerebellar tonsils
  • Chiari I malformation
  • Natural history

ASJC Scopus subject areas

  • Psychiatry and Mental health
  • Clinical Neurology
  • Dermatology

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