Investigations on T cell receptor δ chain (TcR δ) gene expression in freshly isolated normal large granular lymphocytes, natural killer (NK) cell clones and NK bulk cultures revealed six Tδ transcripts (3.5, 3.1, 2.2, 2.0, 1.5 and 1.3 kb) which varied in number and relative abundance in the different samples. None of the six known Tδ variable regions was expressed and the Tδ locus was retained in its germ-line configuration. The origin and significance of these NK-associated Tδ transcripts are discussed.
|Number of pages||4|
|Journal||European Journal of Immunology|
|Publication status||Published - Apr 1990|
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