NDM-1: Il superbug?

Translated title of the contribution: NDM-1: The superbug?

Research output: Contribution to journalArticlepeer-review

Abstract

A novel type of carbapenemase, New Delhi metallo β- lactamase-1 (NDM-1), was first identified in 2008 in two Enterobacteriacea isolates, both recovered from a Swedish patient transferred from India. The emergence of NDM-1 is now reported from all continents, often in patients with a history of travel or hospitalization in the Indian subcontinent. The NDM-1 producing Gram-negative bacteria are mainly Enterobacteriaceae, which can cause colonization or fatal infections, with worrying antimicrobial susceptibility profiles: some isolates have developed resistance to practically all available antibiotics. Is the NDM-1 the super-bug? Are we in the post-antibiotic era? This review is a summary of currently available knowledge of NDM-1 that draws attention to future antimicrobial resistance scenarios.

Translated title of the contributionNDM-1: The superbug?
Original languageItalian
Pages (from-to)224-234
Number of pages11
JournalInfezioni in Medicina
Volume19
Issue number4
Publication statusPublished - Dec 2011

ASJC Scopus subject areas

  • Microbiology (medical)
  • Infectious Diseases

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