A novel type of carbapenemase, New Delhi metallo β- lactamase-1 (NDM-1), was first identified in 2008 in two Enterobacteriacea isolates, both recovered from a Swedish patient transferred from India. The emergence of NDM-1 is now reported from all continents, often in patients with a history of travel or hospitalization in the Indian subcontinent. The NDM-1 producing Gram-negative bacteria are mainly Enterobacteriaceae, which can cause colonization or fatal infections, with worrying antimicrobial susceptibility profiles: some isolates have developed resistance to practically all available antibiotics. Is the NDM-1 the super-bug? Are we in the post-antibiotic era? This review is a summary of currently available knowledge of NDM-1 that draws attention to future antimicrobial resistance scenarios.
|Translated title of the contribution||NDM-1: The superbug?|
|Number of pages||11|
|Journal||Infezioni in Medicina|
|Publication status||Published - Dec 2011|
ASJC Scopus subject areas
- Microbiology (medical)
- Infectious Diseases