Near-infrared fundus autofluorescence in multiple evanescent white-dot syndrome

Maurizio Battaglia Parodi, Pierluigi Iacono, Bruno Falcomatà, Gianluigi Bolognesi, Francesco Bandello

Research output: Contribution to journalArticlepeer-review


PURPOSE: To report the near-infrared fundus autofluorescence (NIR-FAF) pattern in 2 cases of multiple evanescent white-dot syndrome (MEWDS).

METHODS: Three consecutive patients with MEWDS underwent a complete ophthalmologic examination, including color photograph, blue-light fundus autofluorescence, NIR-FAF, fluorescein angiography, and indocyanine green angiography (ICGA). Main outcome measure was the identification of NIR-FAF pattern.

RESULTS: Fluorescein angiography showed patchy hyperfluorescence of the whitish dots. Indocyanine green angiography showed hypofluorescent spots throughout the examination. Blue-light fundus autofluorescence disclosed a speckled pattern without extension to the foveal area, whereas NIR-AF showed several hypoautofluorescent lesions involving also the fovea, which corresponded to the whitish dots visible on biomicroscopy and to the hypofluorescent lesions detectable on ICGA.

CONCLUSIONS: Near-infrared fundus autofluorescence is characterized by hypoautofluorescent spots corresponding to the inflammatory lesions typical of MEWDS and can be considered as a valuable noninvasive technique to diagnose and monitor patients with MEWDS.

Original languageEnglish
Pages (from-to)43-46
Number of pages4
JournalEuropean Journal of Ophthalmology
Issue number1
Publication statusPublished - 2015

ASJC Scopus subject areas

  • Medicine(all)


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