Abstract
Laparoscopic procedures have been associated to moderate or severe pain that may require opioids and almost all patients referred shoulder pain. Intraperitoneal instillation of local anaesthetics, as part of a multimodal approach analgesia program, reduces pain intensity and morphine consumption after laparoscopic cholecystectomy. However, direct local anesthetic instillation is not enough to eliminate visceral and shoulder pain. Heated and humidified gas may produce positive effects such as reduction of postoperative pain. Intraperitoneal nebulization, a new technique of drug administration, provides homogeneous spread of drugs allowing a better distribution of local anaesthetics throughout the peritoneum. This technique combines the effects of gas conditioning and the analgesic benefits of local anaesthetic instillation. Nebulization of local anaesthetics during different laparoscopic procedures reduced postoperative pain, morphine consumption and allowed earlier mobilization. Future studies should determine, the optimal dose of local anaesthetics, the effect of local anaesthetic nebulization in different clinical settings and its importance on long term clinical outcomes.
| Original language | English |
|---|---|
| Pages (from-to) | 235-238 |
| Number of pages | 4 |
| Journal | European Journal of Pain Supplements |
| Volume | 4 |
| Issue number | 4 |
| DOIs | |
| Publication status | Published - Nov 2010 |
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Keywords
- Laparoscopic surgery
- Multimodal analgesia
- Nebulization
- Postoperative pain
- Visceral pain
ASJC Scopus subject areas
- Anesthesiology and Pain Medicine
Cite this
Nebulization of local anaesthetics in laparoscopic surgery : A new tool for postoperative analgesia. / Ingelmo, Pablo M.; Somaini, Marta; Bucciero, Mario; Allegri, Massimo; Bugada, Dario; Cusato, Maria; Diemunsch, Pierre.
In: European Journal of Pain Supplements, Vol. 4, No. 4, 11.2010, p. 235-238.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Nebulization of local anaesthetics in laparoscopic surgery
T2 - A new tool for postoperative analgesia
AU - Ingelmo, Pablo M.
AU - Somaini, Marta
AU - Bucciero, Mario
AU - Allegri, Massimo
AU - Bugada, Dario
AU - Cusato, Maria
AU - Diemunsch, Pierre
PY - 2010/11
Y1 - 2010/11
N2 - Laparoscopic procedures have been associated to moderate or severe pain that may require opioids and almost all patients referred shoulder pain. Intraperitoneal instillation of local anaesthetics, as part of a multimodal approach analgesia program, reduces pain intensity and morphine consumption after laparoscopic cholecystectomy. However, direct local anesthetic instillation is not enough to eliminate visceral and shoulder pain. Heated and humidified gas may produce positive effects such as reduction of postoperative pain. Intraperitoneal nebulization, a new technique of drug administration, provides homogeneous spread of drugs allowing a better distribution of local anaesthetics throughout the peritoneum. This technique combines the effects of gas conditioning and the analgesic benefits of local anaesthetic instillation. Nebulization of local anaesthetics during different laparoscopic procedures reduced postoperative pain, morphine consumption and allowed earlier mobilization. Future studies should determine, the optimal dose of local anaesthetics, the effect of local anaesthetic nebulization in different clinical settings and its importance on long term clinical outcomes.
AB - Laparoscopic procedures have been associated to moderate or severe pain that may require opioids and almost all patients referred shoulder pain. Intraperitoneal instillation of local anaesthetics, as part of a multimodal approach analgesia program, reduces pain intensity and morphine consumption after laparoscopic cholecystectomy. However, direct local anesthetic instillation is not enough to eliminate visceral and shoulder pain. Heated and humidified gas may produce positive effects such as reduction of postoperative pain. Intraperitoneal nebulization, a new technique of drug administration, provides homogeneous spread of drugs allowing a better distribution of local anaesthetics throughout the peritoneum. This technique combines the effects of gas conditioning and the analgesic benefits of local anaesthetic instillation. Nebulization of local anaesthetics during different laparoscopic procedures reduced postoperative pain, morphine consumption and allowed earlier mobilization. Future studies should determine, the optimal dose of local anaesthetics, the effect of local anaesthetic nebulization in different clinical settings and its importance on long term clinical outcomes.
KW - Laparoscopic surgery
KW - Multimodal analgesia
KW - Nebulization
KW - Postoperative pain
KW - Visceral pain
UR - http://www.scopus.com/inward/record.url?scp=78149360107&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=78149360107&partnerID=8YFLogxK
U2 - 10.1016/j.eujps.2010.09.012
DO - 10.1016/j.eujps.2010.09.012
M3 - Article
VL - 4
SP - 235
EP - 238
JO - European Journal of Pain Supplements
JF - European Journal of Pain Supplements
SN - 1754-3207
IS - 4
ER -