Necrotizing sarcoid granulomatosis of the lung in a 12-year-old boy with an atypical clinical course

Serena Panigada, Nicola Ullmann, Oliviero Sacco, Claudio Gambini, Andrew Bush, Giovanni A. Rossi

Research output: Contribution to journalArticlepeer-review

Abstract

Necrotizing sarcoid granulomatosis (NSG) is a disorder of unknown etiology, rarely described in childhood, belonging to the heterogeneous group of the pulmonary angiitis and granulomatosis. One of the characteristics of NSG is to have typically a benign clinical course with minimal treatment with systemic steroids or even with no therapy at all. Here, we report the case of a boy with a lung consolidation, with morphological and histological features consistent with a diagnosis of NSG. Good clinical and roentgenographic response to high dose prednisone treatment was followed three times by relapses, when steroid treatment was tapered. New lesions were detected in different areas of the lung and not in initially affected area, never previously described in NSG and only rarely in other pulmonary angiitides.

Original languageEnglish
Pages (from-to)831-835
Number of pages5
JournalPediatric Pulmonology
Volume47
Issue number8
DOIs
Publication statusPublished - Aug 2012

Keywords

  • children
  • granulomatosis with polyangiitis
  • pulmonary vasculitis
  • sarcoidosis

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Pulmonary and Respiratory Medicine

Fingerprint Dive into the research topics of 'Necrotizing sarcoid granulomatosis of the lung in a 12-year-old boy with an atypical clinical course'. Together they form a unique fingerprint.

Cite this