Need for High Radiation Dose (≥70 Gy) in Early Postoperative Irradiation After Radical Prostatectomy: A Single-Institution Analysis of 334 High-Risk, Node-Negative Patients

Cesare Cozzarini, Francesco Montorsi, Claudio Fiorino, Filippo Alongi, Angelo Bolognesi, Luigi Filippo Da Pozzo, Giorgio Guazzoni, Massimo Freschi, Marco Roscigno, Vincenzo Scattoni, Patrizio Rigatti, Nadia Di Muzio

Research output: Contribution to journalArticle

79 Citations (Scopus)

Abstract

Purpose: To determine the clinical benefit of high-dose early adjuvant radiotherapy (EART) in high-risk prostate cancer (hrCaP) patients submitted to radical retropubic prostatectomy plus pelvic lymphadenectomy. Patients and Methods: The clinical outcome of 334 hrCaP (pT3-4 and/or positive resection margins) node-negative patients submitted to radical retropubic prostatectomy plus pelvic lymphadenectomy before 2004 was analyzed according to the EART dose delivered to the prostatic bed,

Original languageEnglish
Pages (from-to)966-974
Number of pages9
JournalInternational Journal of Radiation Oncology Biology Physics
Volume75
Issue number4
DOIs
Publication statusPublished - Nov 15 2009

Fingerprint

Prostatectomy
Adjuvant Radiotherapy
Radiation
Lymph Node Excision
dosage
irradiation
radiation therapy
radiation
beds
margins
Prostatic Neoplasms
cancer

Keywords

  • Adjuvant
  • Dose
  • Prostatectomy
  • Prostatic neoplasms
  • Radiotherapy

ASJC Scopus subject areas

  • Cancer Research
  • Oncology
  • Radiology Nuclear Medicine and imaging
  • Radiation

Cite this

Need for High Radiation Dose (≥70 Gy) in Early Postoperative Irradiation After Radical Prostatectomy : A Single-Institution Analysis of 334 High-Risk, Node-Negative Patients. / Cozzarini, Cesare; Montorsi, Francesco; Fiorino, Claudio; Alongi, Filippo; Bolognesi, Angelo; Da Pozzo, Luigi Filippo; Guazzoni, Giorgio; Freschi, Massimo; Roscigno, Marco; Scattoni, Vincenzo; Rigatti, Patrizio; Di Muzio, Nadia.

In: International Journal of Radiation Oncology Biology Physics, Vol. 75, No. 4, 15.11.2009, p. 966-974.

Research output: Contribution to journalArticle

Cozzarini, Cesare ; Montorsi, Francesco ; Fiorino, Claudio ; Alongi, Filippo ; Bolognesi, Angelo ; Da Pozzo, Luigi Filippo ; Guazzoni, Giorgio ; Freschi, Massimo ; Roscigno, Marco ; Scattoni, Vincenzo ; Rigatti, Patrizio ; Di Muzio, Nadia. / Need for High Radiation Dose (≥70 Gy) in Early Postoperative Irradiation After Radical Prostatectomy : A Single-Institution Analysis of 334 High-Risk, Node-Negative Patients. In: International Journal of Radiation Oncology Biology Physics. 2009 ; Vol. 75, No. 4. pp. 966-974.
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