Negative correlation between ICA persistence and beta cell restoration after IDDM diagnosis

R. Manna, M. Salvatore, F. Scuderi, G. Papa, G. Marietti, A. V. Greco, G. Ghirlanda, G. Gambassi

Research output: Contribution to journalArticle

Abstract

We have studied 27 insulin-dependent diabetic patients since diagnosis for a period of six months; at diabetes onset and later on, ICA were found in 17 of them, whereas they were undetectable in 10 patients: age was remarkably homogeneous in the two groups. At diabetes onset, no significant differences were found in insulin requirement between ICA positive and ICA negative patients; however, six months after diagnosis, we observed that insulin requirement to keep metabolic control was significantly higher in ICA positive than in ICA negative subjects (0.515±0.2 U/Kg versus 0.22±0.15 U/Kg, p

Original languageEnglish
Pages (from-to)101-103
Number of pages3
JournalDiabetes Research
Volume9
Issue number3
Publication statusPublished - 1988

ASJC Scopus subject areas

  • Endocrinology
  • Endocrinology, Diabetes and Metabolism
  • Internal Medicine

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    Manna, R., Salvatore, M., Scuderi, F., Papa, G., Marietti, G., Greco, A. V., Ghirlanda, G., & Gambassi, G. (1988). Negative correlation between ICA persistence and beta cell restoration after IDDM diagnosis. Diabetes Research, 9(3), 101-103.