Negative predictors of survival in HIV-infected patients with culture-confirmed pulmonary tuberculosis

F. Palmieri, A. M. Pellicelli, E. Girardi, A. P. De Felici, P. De Mori, N. Petrosillo, G. Ippolito

Research output: Contribution to journalArticle

Abstract

We performed a retrospective study based on chart review of 118 HIV-infected patients with culture-confirmed pulmonary TB, in which M. tuberculosis isolates were tested for drug susceptibility. Patients were enrolled in the period January 1987 to December 1996 and followed until September 1997. The median survival for the entire cohort was 15.2 months with a 1-year survival rate of 57%. Prior AIDS-defining illness, low CD4 count (<200/mm3), not having received antituberculous therapy with at least two drugs to which M. tuberculosis was susceptible in vitro, starting within four weeks of diagnosis, treatment duration of less than three weeks and multidrug resistant tuberculosis were each independently associated with decreased survival in multivariate analysis.

Original languageEnglish
Pages (from-to)331-334
Number of pages4
JournalInfection
Volume27
Issue number6
DOIs
Publication statusPublished - 1999

Keywords

  • Drug-resistant tuberculosis
  • HIV infections
  • Prognosis
  • Survival
  • Tuberculosis

ASJC Scopus subject areas

  • Microbiology (medical)
  • Immunology

Fingerprint Dive into the research topics of 'Negative predictors of survival in HIV-infected patients with culture-confirmed pulmonary tuberculosis'. Together they form a unique fingerprint.

  • Cite this