TY - JOUR
T1 - Neonatal Jaundice in Low- and Middle-Income Countries
T2 - Lessons and Future Directions from the 2015 Don Ostrow Trieste Yellow Retreat
AU - Greco, Chiara
AU - Arnolda, Gaston
AU - Boo, Nem Yun
AU - Iskander, Iman F.
AU - Okolo, Angela A.
AU - Rohsiswatmo, Rinawati
AU - Shapiro, Steven M.
AU - Watchko, Jon
AU - Wennberg, Richard P.
AU - Tiribelli, Claudio
AU - Coda Zabetta, Carlos D.
PY - 2016/5/14
Y1 - 2016/5/14
N2 - Severe neonatal hyperbilirubinemia, defined as total serum bilirubin (TSB) ≥20 mg/dl, is associated with a higher risk of permanent neurological sequelae and death. Jaundice can and should be promptly diagnosed and treated. Reliable methods for TSB assay are not always readily available, particularly in low- and middle-income countries, making the true incidence of severe neonatal jaundice (NNJ) difficult to estimate. To gather a more comprehensive picture, a symposium addressing NNJ worldwide was organized during the 2015 Don Ostrow Trieste Yellow Retreat. Data collected by several researchers in different regions of the world were presented and differences/similarities discussed. This report points out the need for: (1) a coordinated worldwide effort to define the burden and the causes of severe NNJ and its consequences; (2) aggressive educational programs for families and health personnel to facilitate timely care-seeking, and (3) accurate diagnostics and effective phototherapy.
AB - Severe neonatal hyperbilirubinemia, defined as total serum bilirubin (TSB) ≥20 mg/dl, is associated with a higher risk of permanent neurological sequelae and death. Jaundice can and should be promptly diagnosed and treated. Reliable methods for TSB assay are not always readily available, particularly in low- and middle-income countries, making the true incidence of severe neonatal jaundice (NNJ) difficult to estimate. To gather a more comprehensive picture, a symposium addressing NNJ worldwide was organized during the 2015 Don Ostrow Trieste Yellow Retreat. Data collected by several researchers in different regions of the world were presented and differences/similarities discussed. This report points out the need for: (1) a coordinated worldwide effort to define the burden and the causes of severe NNJ and its consequences; (2) aggressive educational programs for families and health personnel to facilitate timely care-seeking, and (3) accurate diagnostics and effective phototherapy.
KW - Acute bilirubin encephalopathy
KW - Kernicterus
KW - Low- and middle-income countries
KW - Neonatal jaundice
KW - Severe hyperbilirubinemia
UR - http://www.scopus.com/inward/record.url?scp=84966784692&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84966784692&partnerID=8YFLogxK
U2 - 10.1159/000445708
DO - 10.1159/000445708
M3 - Article
AN - SCOPUS:84966784692
SP - 172
EP - 180
JO - Neonatology
JF - Neonatology
SN - 1661-7800
ER -