Neonatal RIFLE

Zaccaria Ricci, Claudio Ronco

Research output: Contribution to journalArticlepeer-review


A standardized classification of acute kidney injury (AKI) has recently been proposed with the RIFLE (Risk, Injury, Failure, Loss of function, End-stage kidney disease) score. Such definition/classification has been applied both in adult and in paediatric patients. Neonatal definition of AKI likely results as a challenging task due to the peculiar renal pathophysiology of newborn critically ill patients. Their so-called 'immature kidneys' require careful management and neonatal AKI is frequently complicated by unfavourable outcomes. A recent attempt to implement the RIFLE score with a neonatal modification might lead to improvement on the knowledge of AKI incidence and epidemiology.

Original languageEnglish
Pages (from-to)2211-2214
Number of pages4
JournalNephrology Dialysis Transplantation
Issue number9
Publication statusPublished - Sep 2013


  • Acute kidney injury
  • Classification
  • Definition
  • RIFLE score

ASJC Scopus subject areas

  • Nephrology
  • Transplantation


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