Neonatal stroke

M. A. Rutherford; L. A. Ramenghi; F. M. Cowan

doi:10.1136/adc.2010.196451

Neonatal stroke

M. A. Rutherford, L. A. Ramenghi, F. M. Cowan

Fondazione IRCCS Ca' Granda- Ospedale Maggiore Policlinico

Research output: Contribution to journal › Article › peer-review

Abstract

Neonatal stroke encompasses a range of focal and multifocal ischaemic and haemorrhagic tissue injuries. This review will concentrate on focal brain injury that occurs as a consequence of arterial infarction, most frequently the left middle cerebral artery, or more rarely as a consequence of cerebral sinus venous thrombosis (CSVT). Both conditions are multifactorial in origin. The incidence of both acquired and genetic thrombophilic disorders in both mothers and infants is high although rarely causal in isolation. Neurodevelopmental morbidity occurs in over 50% of children. Specific therapy in the form of anticoagulation is currently only recommended in CSVT and needs to be carefully monitored in the presence of haemorrhage. Copyright Article author (or their employer) 2011.

Original language	English
Journal	Archives of Disease in Childhood: Fetal and Neonatal Edition
DOIs	https://doi.org/10.1136/adc.2010.196451
Publication status	Accepted/In press - Aug 17 2011

ASJC Scopus subject areas

Obstetrics and Gynaecology
Pediatrics, Perinatology, and Child Health

Access to Document

10.1136/adc.2010.196451

Cite this

@article{216e2981a2d942c1a09d798e0f58458b,

title = "Neonatal stroke",

abstract = "Neonatal stroke encompasses a range of focal and multifocal ischaemic and haemorrhagic tissue injuries. This review will concentrate on focal brain injury that occurs as a consequence of arterial infarction, most frequently the left middle cerebral artery, or more rarely as a consequence of cerebral sinus venous thrombosis (CSVT). Both conditions are multifactorial in origin. The incidence of both acquired and genetic thrombophilic disorders in both mothers and infants is high although rarely causal in isolation. Neurodevelopmental morbidity occurs in over 50% of children. Specific therapy in the form of anticoagulation is currently only recommended in CSVT and needs to be carefully monitored in the presence of haemorrhage. Copyright Article author (or their employer) 2011.",

author = "Rutherford, {M. A.} and Ramenghi, {L. A.} and Cowan, {F. M.}",

year = "2011",

month = aug,

day = "17",

doi = "10.1136/adc.2010.196451",

language = "English",

journal = "Archives of Disease in Childhood: Fetal and Neonatal Edition",

issn = "1359-2998",

publisher = "BMJ Publishing Group",

}

TY - JOUR

T1 - Neonatal stroke

AU - Rutherford, M. A.

AU - Ramenghi, L. A.

AU - Cowan, F. M.

PY - 2011/8/17

Y1 - 2011/8/17

N2 - Neonatal stroke encompasses a range of focal and multifocal ischaemic and haemorrhagic tissue injuries. This review will concentrate on focal brain injury that occurs as a consequence of arterial infarction, most frequently the left middle cerebral artery, or more rarely as a consequence of cerebral sinus venous thrombosis (CSVT). Both conditions are multifactorial in origin. The incidence of both acquired and genetic thrombophilic disorders in both mothers and infants is high although rarely causal in isolation. Neurodevelopmental morbidity occurs in over 50% of children. Specific therapy in the form of anticoagulation is currently only recommended in CSVT and needs to be carefully monitored in the presence of haemorrhage. Copyright Article author (or their employer) 2011.

AB - Neonatal stroke encompasses a range of focal and multifocal ischaemic and haemorrhagic tissue injuries. This review will concentrate on focal brain injury that occurs as a consequence of arterial infarction, most frequently the left middle cerebral artery, or more rarely as a consequence of cerebral sinus venous thrombosis (CSVT). Both conditions are multifactorial in origin. The incidence of both acquired and genetic thrombophilic disorders in both mothers and infants is high although rarely causal in isolation. Neurodevelopmental morbidity occurs in over 50% of children. Specific therapy in the form of anticoagulation is currently only recommended in CSVT and needs to be carefully monitored in the presence of haemorrhage. Copyright Article author (or their employer) 2011.

UR - http://www.scopus.com/inward/record.url?scp=80051791260&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=80051791260&partnerID=8YFLogxK

U2 - 10.1136/adc.2010.196451

DO - 10.1136/adc.2010.196451

M3 - Article

JO - Archives of Disease in Childhood: Fetal and Neonatal Edition

JF - Archives of Disease in Childhood: Fetal and Neonatal Edition

SN - 1359-2998

ER -

Neonatal stroke

Abstract

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this