Neovaginal mucosa after Vecchietti's laparoscopic operation for Rokitansky syndrome: Structural and ultrastructural study

Luigi Fedele, Stefano Bianchi, Nicola Berlanda, Eleonora Fontana, Ricciarda Raffaelli, Alessandro Bulfoni, Paola Braidotti

Research output: Contribution to journalArticlepeer-review

Abstract

Objective: This study was undertaken to evaluate structural and ultrastructural characteristics of the mucosa of neovaginae created by Vecchietti's laparoscopic operation for Rokitansky syndrome. Study design: Vaginoscopy and Schiller test were performed 3, 6, and 12 months after the operation in 106 patients. A biopsy specimen of the neovagina obtained 12 to 18 months after surgery in 19 patients was examined by light, scanning electron, and transmission electron microscopy. Results: At vaginoscopy, the neovaginal mucosa appeared smooth, lacking the folds that characterize the normal vagina; 12 months after the operation, an iodium-positive epithelium was present in all neovaginae. Mild ultrastructural modifications, as compared with normal vaginal mucosa, were reduced maturation, inflammatory infiltration, and tendency to superficial desquamation. Conclusion: At a 12-month follow-up, the mucosa of neovaginae created by the Vecchietti technique is comparable to the normal vaginal mucosa, with mild structural and ultrastructural modifications that we believe might be due to reduced vascularization.

Original languageEnglish
Pages (from-to)56-61
Number of pages6
JournalAmerican Journal of Obstetrics and Gynecology
Volume195
Issue number1
DOIs
Publication statusPublished - Jul 2006

Keywords

  • Neovaginal mucosa
  • Rokitansky syndrome
  • Vecchietti's operation

ASJC Scopus subject areas

  • Medicine(all)
  • Obstetrics and Gynaecology

Fingerprint Dive into the research topics of 'Neovaginal mucosa after Vecchietti's laparoscopic operation for Rokitansky syndrome: Structural and ultrastructural study'. Together they form a unique fingerprint.

Cite this