Nephrotic syndrome in a mother and her infant: Relationship with cytomegalovirus infection

Marisa Giani, Alberto Edefonti, Beatrice Damiani, Giuseppina Marra, Daniela Colombo, Giovanni Banfi, Emilio Rivolta, Erich H. Strøm, Michael Mihatsch

Research output: Contribution to journalArticlepeer-review

Abstract

This case report describes infantile nephrotic syndrome (NS) in a baby girl with a clinically severe cytomegalovirus (CMV) infection. Culture of the baby's urine was positive for CMV and IgM anti-CMV antibodies were detected, After an unsuccessful course of corticosteroids, gancyclovir treatment was started and a remission of cutaneous, pulmonary, and renal symptoms was achieved. As the mother also developed NS at the end of pregnancy, a common etiology could be postulated, although there were no signs of recent CMV infection in the mother, only anti-CMV IgG. The relationship between CMV infection and glomerular disease is still unclear; NS may represent another manifestation of CMV disease.

Original languageEnglish
Pages (from-to)73-75
Number of pages3
JournalPediatric Nephrology
Volume10
Issue number1
DOIs
Publication statusPublished - Feb 1996

Keywords

  • Cytomegalovirus infection
  • Infantile nephrotic syndrome
  • Pregnancy

ASJC Scopus subject areas

  • Nephrology
  • Pediatrics, Perinatology, and Child Health

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