Nerve growth factor and pain

Paola Sarchielli, Katiuscia Nardi, Stefano Caproni, Davide Chiasserini, Alessio Pieroni, Ilenia Corbelli, Paolo Calabresi

Research output: Book/ReportBook

Abstract

Nerve growth factor (NGF) has a key role not only in the development of sensory and autonomic neurons, but also in the processes of nociception. Several central and peripheral mechanisms have been postulated as the basis of effects of NGF in nociceptive pathways. It has been implicated both in inflammatory and neuropathic pain mechanisms and strategies against NGF, its receptors, and down-stream intracellular signaling activated by this neurotrophin (NT) have been proposed for the treatment of these pathological conditions. This new book examines recent evidence of the involvement of NGF in painful diseases and suggests the potential usefulness of anti-NGF strategies as novel analgesics for these disabling pathological conditions.

Original languageEnglish
PublisherNova Science Publishers, Inc.
Number of pages69
ISBN (Print)9781616682644
Publication statusPublished - 2011

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ASJC Scopus subject areas

  • Medicine(all)

Cite this

Sarchielli, P., Nardi, K., Caproni, S., Chiasserini, D., Pieroni, A., Corbelli, I., & Calabresi, P. (2011). Nerve growth factor and pain. Nova Science Publishers, Inc.