Nerve supply and experimental myotonia in rats

M. R. Caccia; A. Boiardi; L. Andreussi; F. Cornelio

doi:10.1016/0022-510X(75)90230-0

Nerve supply and experimental myotonia in rats

M. R. Caccia, A. Boiardi, L. Andreussi, F. Cornelio

Fondazione IRCCS Istituto Neurologico "C. Besta"

Research output: Contribution to journal › Article › peer-review

Abstract

20,25-Diazacholesterol does not induce myotonia in denervated mammalian skeletal muscle, and cordotomy also renders the muscles resistant to the induction of myotonia. Denervation of muscle already rendered myotonic, has no effect on the intensity of the phenomenon. Finally, tenotomy and posterior rhizotomy leave the myotonic activity in the "deafferentated" muscles unchanged. These findings are discussed in relation to "trophic" influences of the motor pathways on the postsynaptic structures of skeletal muscle.

Original language	English
Pages (from-to)	145-150
Number of pages	6
Journal	Journal of the Neurological Sciences
Volume	24
Issue number	2
DOIs	https://doi.org/10.1016/0022-510X(75)90230-0
Publication status	Published - 1975

ASJC Scopus subject areas

Ageing
Clinical Neurology
Surgery
Neuroscience(all)
Developmental Neuroscience
Neurology

Access to Document

10.1016/0022-510X(75)90230-0

Fingerprint Dive into the research topics of 'Nerve supply and experimental myotonia in rats'. Together they form a unique fingerprint.

Cite this

@article{5edddbfe9a044341a8b9254939e8c650,

title = "Nerve supply and experimental myotonia in rats",

abstract = "20,25-Diazacholesterol does not induce myotonia in denervated mammalian skeletal muscle, and cordotomy also renders the muscles resistant to the induction of myotonia. Denervation of muscle already rendered myotonic, has no effect on the intensity of the phenomenon. Finally, tenotomy and posterior rhizotomy leave the myotonic activity in the {"}deafferentated{"} muscles unchanged. These findings are discussed in relation to {"}trophic{"} influences of the motor pathways on the postsynaptic structures of skeletal muscle.",

author = "Caccia, {M. R.} and A. Boiardi and L. Andreussi and F. Cornelio",

year = "1975",

doi = "10.1016/0022-510X(75)90230-0",

language = "English",

volume = "24",

pages = "145--150",

journal = "Journal of the Neurological Sciences",

issn = "0022-510X",

publisher = "Elsevier",

number = "2",

}

TY - JOUR

T1 - Nerve supply and experimental myotonia in rats

AU - Caccia, M. R.

AU - Boiardi, A.

AU - Andreussi, L.

AU - Cornelio, F.

PY - 1975

Y1 - 1975

N2 - 20,25-Diazacholesterol does not induce myotonia in denervated mammalian skeletal muscle, and cordotomy also renders the muscles resistant to the induction of myotonia. Denervation of muscle already rendered myotonic, has no effect on the intensity of the phenomenon. Finally, tenotomy and posterior rhizotomy leave the myotonic activity in the "deafferentated" muscles unchanged. These findings are discussed in relation to "trophic" influences of the motor pathways on the postsynaptic structures of skeletal muscle.

AB - 20,25-Diazacholesterol does not induce myotonia in denervated mammalian skeletal muscle, and cordotomy also renders the muscles resistant to the induction of myotonia. Denervation of muscle already rendered myotonic, has no effect on the intensity of the phenomenon. Finally, tenotomy and posterior rhizotomy leave the myotonic activity in the "deafferentated" muscles unchanged. These findings are discussed in relation to "trophic" influences of the motor pathways on the postsynaptic structures of skeletal muscle.

UR - http://www.scopus.com/inward/record.url?scp=0016431453&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0016431453&partnerID=8YFLogxK

U2 - 10.1016/0022-510X(75)90230-0

DO - 10.1016/0022-510X(75)90230-0

M3 - Article

C2 - 163298

AN - SCOPUS:0016431453

VL - 24

SP - 145

EP - 150

JO - Journal of the Neurological Sciences

JF - Journal of the Neurological Sciences

SN - 0022-510X

IS - 2

ER -