Nerve terminal remodeling visualized in living mice by repeated examination of the same neuron

Dale Purves, James T. Voyvodic, Lorenzo Magrassi, Hiromu Yawo

Research output: Contribution to journalArticlepeer-review

Abstract

The distribution of presynaptic endings on the surfaces of autonomic ganglion cells was mapped in living mice after intravenous administration of a styryl pyridinium dye. The staining and imaging techniques did not appear to damage the ganglion cells, or the synapses on them; these procedures could therefore be repeated after an arbitrary period. Observations of the same neurons at intervals of up to 3 weeks indicate that the pattern of preganglionic terminals on many of these nerve cells gradually changes.

Original languageEnglish
Pages (from-to)1122-1126
Number of pages5
JournalScience
Volume238
Issue number4830
Publication statusPublished - 1987

ASJC Scopus subject areas

  • General

Fingerprint Dive into the research topics of 'Nerve terminal remodeling visualized in living mice by repeated examination of the same neuron'. Together they form a unique fingerprint.

Cite this