TY - JOUR
T1 - Network Of Cancer Genes
T2 - A web resource to analyze duplicability, orthology and network properties of cancer genes
AU - Syed, Adnan S.
AU - D'Antonio, Matteo
AU - Ciccarelli, Francesca D.
PY - 2009/11/11
Y1 - 2009/11/11
N2 - The Network of Cancer Genes (NCG) collects and integrates data on 736 human genes that are mutated in various types of cancer. For each gene, NCG provides information on duplicability, orthology, evolutionary appearance and topological properties of the encoded protein in a comprehensive version of the human protein-protein interaction network. NCG also stores information on all primary interactors of cancer proteins, thus providing a complete overview of 5357 proteins that constitute direct and indirect determinants of human cancer. With the constant delivery of results from the mutational screenings of cancer genomes, NCG represents a versatile resource for retrieving detailed information on particular cancer genes, as well as for identifying common properties of precompiled lists of cancer genes. NCG is freely available at: http://bio.ifom-ieo-campus.it/ncg.
AB - The Network of Cancer Genes (NCG) collects and integrates data on 736 human genes that are mutated in various types of cancer. For each gene, NCG provides information on duplicability, orthology, evolutionary appearance and topological properties of the encoded protein in a comprehensive version of the human protein-protein interaction network. NCG also stores information on all primary interactors of cancer proteins, thus providing a complete overview of 5357 proteins that constitute direct and indirect determinants of human cancer. With the constant delivery of results from the mutational screenings of cancer genomes, NCG represents a versatile resource for retrieving detailed information on particular cancer genes, as well as for identifying common properties of precompiled lists of cancer genes. NCG is freely available at: http://bio.ifom-ieo-campus.it/ncg.
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U2 - 10.1093/nar/gkp957
DO - 10.1093/nar/gkp957
M3 - Article
C2 - 19906700
AN - SCOPUS:75549089911
VL - 38
JO - Nucleic Acids Research
JF - Nucleic Acids Research
SN - 0305-1048
IS - SUPPL.1
M1 - gkp957
ER -