Neural Activations during Visual Sequence Learning Leave a Trace in Post-Training Spontaneous EEG

Clara Moisello, Hadj Boumediene Meziane, Simon Kelly, Bernardo Perfetti, Svetlana Kvint, Nicholas Voutsinas, Daniella Blanco, Angelo Quartarone, Giulio Tononi, Maria Felice Ghilardi

Research output: Contribution to journalArticle

14 Citations (Scopus)

Abstract

Recent EEG studies have shown that implicit learning involving specific cortical circuits results in an enduring local trace manifested as local changes in spectral power. Here we used a well characterized visual sequence learning task and high density-(hd-)EEG recording to determine whether also declarative learning leaves a post-task, local change in the resting state oscillatory activity in the areas involved in the learning process. Thus, we recorded hd-EEG in normal subjects before, during and after the acquisition of the order of a fixed spatial target sequence (VSEQ) and during the presentation of targets in random order (VRAN). We first determined the temporal evolution of spectral changes during VSEQ and compared it to VRAN. We found significant differences in the alpha and theta bands in three main scalp regions, a right occipito-parietal (ROP), an anterior-frontal (AFr), and a right frontal (RFr) area. The changes in frontal theta power during VSEQ were positively correlated with the learning rate. Further, post-learning EEG recordings during resting state revealed a significant increase in alpha power in ROP relative to a pre-learning baseline. We conclude that declarative learning is associated with alpha and theta changes in frontal and posterior regions that occur during the task, and with an increase of alpha power in the occipito-parietal region after the task. These post-task changes may represent a trace of learning and a hallmark of use-dependent plasticity.

Original languageEnglish
Article numbere65882
JournalPLoS One
Volume8
Issue number6
DOIs
Publication statusPublished - Jun 14 2013

Fingerprint

Electroencephalography
learning
Chemical activation
Learning
Plasticity
Networks (circuits)
Parietal Lobe
Scalp
Power (Psychology)

ASJC Scopus subject areas

  • Agricultural and Biological Sciences(all)
  • Biochemistry, Genetics and Molecular Biology(all)
  • Medicine(all)

Cite this

Moisello, C., Meziane, H. B., Kelly, S., Perfetti, B., Kvint, S., Voutsinas, N., ... Ghilardi, M. F. (2013). Neural Activations during Visual Sequence Learning Leave a Trace in Post-Training Spontaneous EEG. PLoS One, 8(6), [e65882]. https://doi.org/10.1371/journal.pone.0065882

Neural Activations during Visual Sequence Learning Leave a Trace in Post-Training Spontaneous EEG. / Moisello, Clara; Meziane, Hadj Boumediene; Kelly, Simon; Perfetti, Bernardo; Kvint, Svetlana; Voutsinas, Nicholas; Blanco, Daniella; Quartarone, Angelo; Tononi, Giulio; Ghilardi, Maria Felice.

In: PLoS One, Vol. 8, No. 6, e65882, 14.06.2013.

Research output: Contribution to journalArticle

Moisello, C, Meziane, HB, Kelly, S, Perfetti, B, Kvint, S, Voutsinas, N, Blanco, D, Quartarone, A, Tononi, G & Ghilardi, MF 2013, 'Neural Activations during Visual Sequence Learning Leave a Trace in Post-Training Spontaneous EEG', PLoS One, vol. 8, no. 6, e65882. https://doi.org/10.1371/journal.pone.0065882
Moisello C, Meziane HB, Kelly S, Perfetti B, Kvint S, Voutsinas N et al. Neural Activations during Visual Sequence Learning Leave a Trace in Post-Training Spontaneous EEG. PLoS One. 2013 Jun 14;8(6). e65882. https://doi.org/10.1371/journal.pone.0065882
Moisello, Clara ; Meziane, Hadj Boumediene ; Kelly, Simon ; Perfetti, Bernardo ; Kvint, Svetlana ; Voutsinas, Nicholas ; Blanco, Daniella ; Quartarone, Angelo ; Tononi, Giulio ; Ghilardi, Maria Felice. / Neural Activations during Visual Sequence Learning Leave a Trace in Post-Training Spontaneous EEG. In: PLoS One. 2013 ; Vol. 8, No. 6.
@article{dd17ce0904604c229b1113d1bbde37c5,
title = "Neural Activations during Visual Sequence Learning Leave a Trace in Post-Training Spontaneous EEG",
abstract = "Recent EEG studies have shown that implicit learning involving specific cortical circuits results in an enduring local trace manifested as local changes in spectral power. Here we used a well characterized visual sequence learning task and high density-(hd-)EEG recording to determine whether also declarative learning leaves a post-task, local change in the resting state oscillatory activity in the areas involved in the learning process. Thus, we recorded hd-EEG in normal subjects before, during and after the acquisition of the order of a fixed spatial target sequence (VSEQ) and during the presentation of targets in random order (VRAN). We first determined the temporal evolution of spectral changes during VSEQ and compared it to VRAN. We found significant differences in the alpha and theta bands in three main scalp regions, a right occipito-parietal (ROP), an anterior-frontal (AFr), and a right frontal (RFr) area. The changes in frontal theta power during VSEQ were positively correlated with the learning rate. Further, post-learning EEG recordings during resting state revealed a significant increase in alpha power in ROP relative to a pre-learning baseline. We conclude that declarative learning is associated with alpha and theta changes in frontal and posterior regions that occur during the task, and with an increase of alpha power in the occipito-parietal region after the task. These post-task changes may represent a trace of learning and a hallmark of use-dependent plasticity.",
author = "Clara Moisello and Meziane, {Hadj Boumediene} and Simon Kelly and Bernardo Perfetti and Svetlana Kvint and Nicholas Voutsinas and Daniella Blanco and Angelo Quartarone and Giulio Tononi and Ghilardi, {Maria Felice}",
year = "2013",
month = "6",
day = "14",
doi = "10.1371/journal.pone.0065882",
language = "English",
volume = "8",
journal = "PLoS One",
issn = "1932-6203",
publisher = "Public Library of Science",
number = "6",

}

TY - JOUR

T1 - Neural Activations during Visual Sequence Learning Leave a Trace in Post-Training Spontaneous EEG

AU - Moisello, Clara

AU - Meziane, Hadj Boumediene

AU - Kelly, Simon

AU - Perfetti, Bernardo

AU - Kvint, Svetlana

AU - Voutsinas, Nicholas

AU - Blanco, Daniella

AU - Quartarone, Angelo

AU - Tononi, Giulio

AU - Ghilardi, Maria Felice

PY - 2013/6/14

Y1 - 2013/6/14

N2 - Recent EEG studies have shown that implicit learning involving specific cortical circuits results in an enduring local trace manifested as local changes in spectral power. Here we used a well characterized visual sequence learning task and high density-(hd-)EEG recording to determine whether also declarative learning leaves a post-task, local change in the resting state oscillatory activity in the areas involved in the learning process. Thus, we recorded hd-EEG in normal subjects before, during and after the acquisition of the order of a fixed spatial target sequence (VSEQ) and during the presentation of targets in random order (VRAN). We first determined the temporal evolution of spectral changes during VSEQ and compared it to VRAN. We found significant differences in the alpha and theta bands in three main scalp regions, a right occipito-parietal (ROP), an anterior-frontal (AFr), and a right frontal (RFr) area. The changes in frontal theta power during VSEQ were positively correlated with the learning rate. Further, post-learning EEG recordings during resting state revealed a significant increase in alpha power in ROP relative to a pre-learning baseline. We conclude that declarative learning is associated with alpha and theta changes in frontal and posterior regions that occur during the task, and with an increase of alpha power in the occipito-parietal region after the task. These post-task changes may represent a trace of learning and a hallmark of use-dependent plasticity.

AB - Recent EEG studies have shown that implicit learning involving specific cortical circuits results in an enduring local trace manifested as local changes in spectral power. Here we used a well characterized visual sequence learning task and high density-(hd-)EEG recording to determine whether also declarative learning leaves a post-task, local change in the resting state oscillatory activity in the areas involved in the learning process. Thus, we recorded hd-EEG in normal subjects before, during and after the acquisition of the order of a fixed spatial target sequence (VSEQ) and during the presentation of targets in random order (VRAN). We first determined the temporal evolution of spectral changes during VSEQ and compared it to VRAN. We found significant differences in the alpha and theta bands in three main scalp regions, a right occipito-parietal (ROP), an anterior-frontal (AFr), and a right frontal (RFr) area. The changes in frontal theta power during VSEQ were positively correlated with the learning rate. Further, post-learning EEG recordings during resting state revealed a significant increase in alpha power in ROP relative to a pre-learning baseline. We conclude that declarative learning is associated with alpha and theta changes in frontal and posterior regions that occur during the task, and with an increase of alpha power in the occipito-parietal region after the task. These post-task changes may represent a trace of learning and a hallmark of use-dependent plasticity.

UR - http://www.scopus.com/inward/record.url?scp=84879175129&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84879175129&partnerID=8YFLogxK

U2 - 10.1371/journal.pone.0065882

DO - 10.1371/journal.pone.0065882

M3 - Article

VL - 8

JO - PLoS One

JF - PLoS One

SN - 1932-6203

IS - 6

M1 - e65882

ER -