Neural control of cardiovascular function: a case study on a patient carrying a left ventricular assist device

R. Maestri, A. Mortara, S. Scuri, G. D. Pinna

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

We analyzed by spectral techniques the cardiovascular variability signals recorded in a patient carrying a left ventricular assist device. This device, while constituting a simplified model of the cardiovascular function, allows the accurate recording of beat-by-beat stroke volume. We recorded 8 min of: the native heart RR intervals, the pump cycle duration (PCD), the stroke volume (SV), the systolic and diastolic blood pressure (SP, DP), the instantaneous lung volume (ILV) and the arterial O2 saturation (SpO2). We found a dominant respiratory peak (0.32 Hz, HF peak) in the SV and PCD while SP, DP, RR and LV showed both the HF peak and a spectral component around 0.02 Hz (VLF peak). Finally, SpO2 was characterized only by the VLF peak. The coherence was high (>0.8) between all signals at the HF peak and from moderate (0.5-0.6) to high, depending on the signals considered, at the VLF peak. The presence of a VLF oscillation in the SP and DP but not in the SV nor in the PCD supported the hypothesis that this pressure oscillation has not simply a mechanical origin due to the venous return to the heart but is caused by a modulation of the vasomotor tone.

Original languageEnglish
Title of host publicationComputers in Cardiology
PublisherIEEE
Pages489-492
Number of pages4
Publication statusPublished - 1995
EventProceedings of the 1995 Conference on Computers in Cardiology - Vienna, Austria
Duration: Sep 10 1995Sep 13 1995

Other

OtherProceedings of the 1995 Conference on Computers in Cardiology
CityVienna, Austria
Period9/10/959/13/95

ASJC Scopus subject areas

  • Software
  • Cardiology and Cardiovascular Medicine

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