Neurally adjusted ventilatory assist and lung transplant in a child: A case report

Vincenzo Vitale, Zaccaria Ricci, Stefano Morelli, Chiara Giorni, Giuseppina Testa, Luca Di Chiara, Giorgio Conti, Sergio Picardo

Research output: Contribution to journalArticlepeer-review


Objective: To report the successful application of neurally adjusted ventilatory assist to a child with cystic fibrosis who underwent single-lung transplantation. Design: Case report. Setting: Pediatric cardiac intensive care unit. PATIENT: A 15-yr-old male with cystic fibrosis was admitted to our pediatric cardiac intensive care unit after single-lung transplantation. The child had previously received two bowel resections at the age of 1 yr, right pneumonectomy at the age of 3 yrs, and endoscopic percutaneus gastrostomy at the age of 10 yrs. After transplant, the child failed several attempts of weaning off mechanical ventilation with pressure-support ventilation, due to infection, pneumothorax, and ventilator asynchrony that caused gastric distension and numerous episodes of nausea and vomiting. INTERVENTION: Use of neurally adjusted ventilatory assist to avoid patient-ventilator yssynchrony and consequent gastric distension. ConclusionS: The utilization of neurally adjusted ventilatory assist allowed to limit the risk of overassistance and prevent patient-ventilator asynchrony and to successfully wean the child off mechanical ventilation after single-lung transplant.

Original languageEnglish
JournalPediatric Critical Care Medicine
Issue number5
Publication statusPublished - Sep 2010


  • gastric distension
  • lung transplant
  • mechanical ventilation
  • neurally adjusted ventilatory assist
  • patient-ventilator asynchrony
  • weaning off mechanical ventilation

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Critical Care and Intensive Care Medicine


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