Neuroadipology: A novel component of neuroendocrinology

George N. Chaldakov, Marco Fiore, Anton B. Tonchev, Luigi Aloe

Research output: Contribution to journalArticle

Abstract

Adipose tissue is a dynamic endocrine and paracrine organ producing a large number of signalling proteins collectively termed adipokines. Some of them are mediators in the cross-talk between adipose tissue and the brain in regulating food intake and energy homoeostasis. However, the hypothalamus is not the only brain target for adipokines, and food intake is not the only biological effect of these signals. Rather, some adipokines support various cognitive functions and exert neurotrophic activity. Current data on adipose-derived neuropeptides, neurotrophic factors, pituitary hormones and hypothalamic releasing factors is highlighted in this review. We propose that adipose tissue is a member of the diffuse neuroendocrine system. Cumulatively, this is conceptualized as neuroadipology, a new example of a link between neurobiology and other topics, such as neuroimmunology and neuroendocrinology. Because adipose tissue is a bona fide endocrine organ, neuroadipology may be considered a new discipline in neuroendocrinology. It may have a wide-ranging potential within a variety of neuronal and metabolic functions in health and disease.

Original languageEnglish
Pages (from-to)1051-1053
Number of pages3
JournalCell Biology International
Volume34
Issue number10
DOIs
Publication statusPublished - Oct 2010

Fingerprint

Neuroendocrinology
Adipokines
Adipose Tissue
Eating
Pituitary Hormone-Releasing Hormones
Neurosecretory Systems
Pituitary Hormones
Neurobiology
Nerve Growth Factors
Brain
Neuropeptides
Cognition
Hypothalamus
Homeostasis
Health
Proteins

Keywords

  • Adipose tissue
  • Diffuse neuroendocrine system
  • Neurotrophic factor

ASJC Scopus subject areas

  • Cell Biology

Cite this

Chaldakov, G. N., Fiore, M., Tonchev, A. B., & Aloe, L. (2010). Neuroadipology: A novel component of neuroendocrinology. Cell Biology International, 34(10), 1051-1053. https://doi.org/10.1042/CBI20100509

Neuroadipology : A novel component of neuroendocrinology. / Chaldakov, George N.; Fiore, Marco; Tonchev, Anton B.; Aloe, Luigi.

In: Cell Biology International, Vol. 34, No. 10, 10.2010, p. 1051-1053.

Research output: Contribution to journalArticle

Chaldakov, GN, Fiore, M, Tonchev, AB & Aloe, L 2010, 'Neuroadipology: A novel component of neuroendocrinology', Cell Biology International, vol. 34, no. 10, pp. 1051-1053. https://doi.org/10.1042/CBI20100509
Chaldakov, George N. ; Fiore, Marco ; Tonchev, Anton B. ; Aloe, Luigi. / Neuroadipology : A novel component of neuroendocrinology. In: Cell Biology International. 2010 ; Vol. 34, No. 10. pp. 1051-1053.
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