Neuroendocrine tumors diagnosed at the "Antonio Cardarelli" hospital (Naples, Campania, Italy) between 2006-2009: A single-institution analysis

Ferdinando Riccardi, O. Nappi, A. Balzano, M. De Palma, C. Buonerba, M. Rizzo, C. Barbato, G. De Dominicis, U. Buonocore, G. De Sena, S. Lastoria, C. Molino, G. Monaco, P. G. Rabitti, L. Romano, F. Scavuzzo, R. Suozzo, G. Uomo, R. Volpe, G. Di LorenzoG. Cartenì

Research output: Contribution to journalArticle

Abstract

Neuroendocrine tumors (NETs) are rare, with an incidence of about 5 per 100,000 inhabitants. As no study on NETs has ever been specifically conducted on the population of Campania, we performed a retrospective analysis of all newly diagnosed NETs at the "Antonio Cardarelli" hospital between 2006-2009. A search of the registry of the Pathology Department of the "Antonio Cardarelli" hospital was carried out to retrieve available data on all newly diagnosed NET cases. Two hundred and ninety-nine NET tumors were diagnosed at our Institution from January, 2006 to December, 2009. Globally, 121 patients (40% of the population) had a lung NET, while 92 patients (30% of the population) presented a GEP-NET. The most common primary tumor site varied by sex, with female patients being more likely to have a primary NET in the lung, breast or colon, and male patients being more likely to have a primary tumor in the lung. Also, twenty-three cases of breast NETs were identified, and clinical information regarding therapy and response was available for 22 patients. Our study represents a pioneering effort to provide the medical community in Campania with basic information on a large number of patients with different types of NETs. The "Antonio Cardarelli" hospital could greatly benefit from cooperation with other hospitals in order to become a highly specialized center for NETs in the region and Southern Italy.

Original languageEnglish
Pages (from-to)251-256
Number of pages6
JournalInternational Journal of Immunopathology and Pharmacology
Volume24
Issue number1
Publication statusPublished - Jan 2011

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Keywords

  • Epidemiologic study
  • Neuroendocrine tumors

ASJC Scopus subject areas

  • Pharmacology
  • Immunology
  • Immunology and Allergy

Cite this

Riccardi, F., Nappi, O., Balzano, A., De Palma, M., Buonerba, C., Rizzo, M., Barbato, C., De Dominicis, G., Buonocore, U., De Sena, G., Lastoria, S., Molino, C., Monaco, G., Rabitti, P. G., Romano, L., Scavuzzo, F., Suozzo, R., Uomo, G., Volpe, R., ... Cartenì, G. (2011). Neuroendocrine tumors diagnosed at the "Antonio Cardarelli" hospital (Naples, Campania, Italy) between 2006-2009: A single-institution analysis. International Journal of Immunopathology and Pharmacology, 24(1), 251-256.