Neurofibromatosis and malignant childhood cancers: a survey in Italy, 1970-83.

M. L. Mosso; M. Castello; F. Fossati Bellani; M. T. Di Tullio; G. Loiacono; G. Paolucci; P. Tamaro; B. Terracini; G. Pastore; F. Loiacono

Neurofibromatosis and malignant childhood cancers: a survey in Italy, 1970-83.

M. L. Mosso, M. Castello, F. Fossati Bellani, M. T. Di Tullio, G. Loiacono, G. Paolucci, P. Tamaro, B. Terracini, G. Pastore, F. Loiacono

IRCCS pediatrico Burlo Garofolo

Research output: Contribution to journal › Article › peer-review

Abstract

Neural tumors, Wilms' tumor, rhabdomyosarcoma and several types of leukemia have been previously described in association with neurofibromatosis (NF). In a nation-wide collection of cases in Italy, 15 children (0-14 years of age) with NF and cancer or leukemia were identified; 13 of them had been diagnosed with cancer between 1976-83. The expected number of children with cancer and NF in 1976-83 was 4.48. The distribution of tumor types was different from that found in the general population, with a higher proportion of tumors of neural crest origin as well as soft tissue sarcomas. In 7/15 the family history was positive for NF; in 5/7 the individuals affected included the mother and/or a maternal relative.

Original language	English
Pages (from-to)	209-212
Number of pages	4
Journal	Tumori
Volume	73
Issue number	3
Publication status	Published - Jun 30 1987

ASJC Scopus subject areas

Cancer Research

Cite this

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title = "Neurofibromatosis and malignant childhood cancers: a survey in Italy, 1970-83.",

abstract = "Neural tumors, Wilms' tumor, rhabdomyosarcoma and several types of leukemia have been previously described in association with neurofibromatosis (NF). In a nation-wide collection of cases in Italy, 15 children (0-14 years of age) with NF and cancer or leukemia were identified; 13 of them had been diagnosed with cancer between 1976-83. The expected number of children with cancer and NF in 1976-83 was 4.48. The distribution of tumor types was different from that found in the general population, with a higher proportion of tumors of neural crest origin as well as soft tissue sarcomas. In 7/15 the family history was positive for NF; in 5/7 the individuals affected included the mother and/or a maternal relative.",

author = "Mosso, {M. L.} and M. Castello and {Fossati Bellani}, F. and {Di Tullio}, {M. T.} and G. Loiacono and G. Paolucci and P. Tamaro and B. Terracini and G. Pastore and F. Loiacono",

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T2 - a survey in Italy, 1970-83.

AU - Mosso, M. L.

AU - Castello, M.

AU - Fossati Bellani, F.

AU - Di Tullio, M. T.

AU - Loiacono, G.

AU - Paolucci, G.

AU - Tamaro, P.

AU - Terracini, B.

AU - Pastore, G.

AU - Loiacono, F.

PY - 1987/6/30

Y1 - 1987/6/30

N2 - Neural tumors, Wilms' tumor, rhabdomyosarcoma and several types of leukemia have been previously described in association with neurofibromatosis (NF). In a nation-wide collection of cases in Italy, 15 children (0-14 years of age) with NF and cancer or leukemia were identified; 13 of them had been diagnosed with cancer between 1976-83. The expected number of children with cancer and NF in 1976-83 was 4.48. The distribution of tumor types was different from that found in the general population, with a higher proportion of tumors of neural crest origin as well as soft tissue sarcomas. In 7/15 the family history was positive for NF; in 5/7 the individuals affected included the mother and/or a maternal relative.

AB - Neural tumors, Wilms' tumor, rhabdomyosarcoma and several types of leukemia have been previously described in association with neurofibromatosis (NF). In a nation-wide collection of cases in Italy, 15 children (0-14 years of age) with NF and cancer or leukemia were identified; 13 of them had been diagnosed with cancer between 1976-83. The expected number of children with cancer and NF in 1976-83 was 4.48. The distribution of tumor types was different from that found in the general population, with a higher proportion of tumors of neural crest origin as well as soft tissue sarcomas. In 7/15 the family history was positive for NF; in 5/7 the individuals affected included the mother and/or a maternal relative.

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Neurofibromatosis and malignant childhood cancers: a survey in Italy, 1970-83.

Abstract

ASJC Scopus subject areas

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