Abstract
Previous studies suggest a localized activation of specific areas in healthy subjects during mental calculation. We report the case of patient affected by calculation-induced seizures that were refractory to medications. We showed the cortical activation by using a functional magnetic resonance imaging (fMRI) while he was performing an arithmetic task and illustrated that, in this case, the areas commonly activated included the premotor and supplementary motor areas of both hemispheres. Furthermore, the patient showed a more significant activation of posterior parietal and prefrontal cortices after arithmetic tasks if compared to normal controls. To our knowledge, this is the first fMRI study in calculation-induced seizures, even if limited to a single patient. The potential benefits of non-conventional neuroimaging technology, such as fMRI, for understanding calculation, however, are only beginning to be tapped.
| Original language | English |
|---|---|
| Pages (from-to) | 505-508 |
| Number of pages | 4 |
| Journal | Neurological Sciences |
| Volume | 30 |
| Issue number | 6 |
| DOIs | |
| Publication status | Published - Dec 2009 |
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Keywords
- Calculations
- Epilepsy
- Functional MRI
ASJC Scopus subject areas
- Clinical Neurology
- Psychiatry and Mental health
- Dermatology
Cite this
Neurofunctional assessment in a case of calculation-induced seizures. / Marino, Silvia; Lanzafame, Pietro; Morabito, Rosa; Pollicino, Patrizia; Muscarà, Nunzio; Bramanti, Placido.
In: Neurological Sciences, Vol. 30, No. 6, 12.2009, p. 505-508.Research output: Contribution to journal › Article
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TY - JOUR
T1 - Neurofunctional assessment in a case of calculation-induced seizures
AU - Marino, Silvia
AU - Lanzafame, Pietro
AU - Morabito, Rosa
AU - Pollicino, Patrizia
AU - Muscarà, Nunzio
AU - Bramanti, Placido
PY - 2009/12
Y1 - 2009/12
N2 - Previous studies suggest a localized activation of specific areas in healthy subjects during mental calculation. We report the case of patient affected by calculation-induced seizures that were refractory to medications. We showed the cortical activation by using a functional magnetic resonance imaging (fMRI) while he was performing an arithmetic task and illustrated that, in this case, the areas commonly activated included the premotor and supplementary motor areas of both hemispheres. Furthermore, the patient showed a more significant activation of posterior parietal and prefrontal cortices after arithmetic tasks if compared to normal controls. To our knowledge, this is the first fMRI study in calculation-induced seizures, even if limited to a single patient. The potential benefits of non-conventional neuroimaging technology, such as fMRI, for understanding calculation, however, are only beginning to be tapped.
AB - Previous studies suggest a localized activation of specific areas in healthy subjects during mental calculation. We report the case of patient affected by calculation-induced seizures that were refractory to medications. We showed the cortical activation by using a functional magnetic resonance imaging (fMRI) while he was performing an arithmetic task and illustrated that, in this case, the areas commonly activated included the premotor and supplementary motor areas of both hemispheres. Furthermore, the patient showed a more significant activation of posterior parietal and prefrontal cortices after arithmetic tasks if compared to normal controls. To our knowledge, this is the first fMRI study in calculation-induced seizures, even if limited to a single patient. The potential benefits of non-conventional neuroimaging technology, such as fMRI, for understanding calculation, however, are only beginning to be tapped.
KW - Calculations
KW - Epilepsy
KW - Functional MRI
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U2 - 10.1007/s10072-009-0121-z
DO - 10.1007/s10072-009-0121-z
M3 - Article
VL - 30
SP - 505
EP - 508
JO - Neurological Sciences
JF - Neurological Sciences
SN - 1590-1874
IS - 6
ER -