Abstract
Muscle hypertrophy is rare in denervating diseases. A patient with calf enlargement associated with L5-S1 radiculopathy and another with thenar, hypothenar, forearm and calf muscle hypertrophy in the course of chronic relapsing inflammatory demyelinating polyneuropathy are described. Gastrocnemius muscle biopsy revealed both type I and type II fibre hypertrophy in the former case and predominant type I fibre hypertrophy in the latter. Passive stretching and abnormal spontaneous muscular activity might have played a role in the origin of hypertrophy in both patients, but a satisfactory explanation for denervation hypertrophy has yet to be provided.
| Original language | English |
|---|---|
| Pages (from-to) | 292-295 |
| Number of pages | 4 |
| Journal | Journal of Neurology |
| Volume | 236 |
| Issue number | 5 |
| DOIs | |
| Publication status | Published - Jul 1989 |
Keywords
- Muscle hypertrophy
- Neuropathies
- Spontaneous muscular activity
- Stretching
ASJC Scopus subject areas
- Neurology
- Clinical Neurology
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Pareyson, D., Morandi, L., Scaioli, V., Marazzi, R., Boiardi, A., & Sghirlanzoni, A. (1989). Neurogenic muscle hypertrophy - Report of two cases. Journal of Neurology, 236(5), 292-295. https://doi.org/10.1007/BF00314459