Abstract
Muscle hypertrophy is rare in denervating diseases. A patient with calf enlargement associated with L5-S1 radiculopathy and another with thenar, hypothenar, forearm and calf muscle hypertrophy in the course of chronic relapsing inflammatory demyelinating polyneuropathy are described. Gastrocnemius muscle biopsy revealed both type I and type II fibre hypertrophy in the former case and predominant type I fibre hypertrophy in the latter. Passive stretching and abnormal spontaneous muscular activity might have played a role in the origin of hypertrophy in both patients, but a satisfactory explanation for denervation hypertrophy has yet to be provided.
| Original language | English |
|---|---|
| Pages (from-to) | 292-295 |
| Number of pages | 4 |
| Journal | Journal of Neurology |
| Volume | 236 |
| Issue number | 5 |
| DOIs | |
| Publication status | Published - Jul 1989 |
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Keywords
- Muscle hypertrophy
- Neuropathies
- Spontaneous muscular activity
- Stretching
ASJC Scopus subject areas
- Neurology
- Clinical Neurology
Cite this
Neurogenic muscle hypertrophy - Report of two cases. / Pareyson, D.; Morandi, L.; Scaioli, V.; Marazzi, R.; Boiardi, A.; Sghirlanzoni, A.
In: Journal of Neurology, Vol. 236, No. 5, 07.1989, p. 292-295.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Neurogenic muscle hypertrophy - Report of two cases
AU - Pareyson, D.
AU - Morandi, L.
AU - Scaioli, V.
AU - Marazzi, R.
AU - Boiardi, A.
AU - Sghirlanzoni, A.
PY - 1989/7
Y1 - 1989/7
N2 - Muscle hypertrophy is rare in denervating diseases. A patient with calf enlargement associated with L5-S1 radiculopathy and another with thenar, hypothenar, forearm and calf muscle hypertrophy in the course of chronic relapsing inflammatory demyelinating polyneuropathy are described. Gastrocnemius muscle biopsy revealed both type I and type II fibre hypertrophy in the former case and predominant type I fibre hypertrophy in the latter. Passive stretching and abnormal spontaneous muscular activity might have played a role in the origin of hypertrophy in both patients, but a satisfactory explanation for denervation hypertrophy has yet to be provided.
AB - Muscle hypertrophy is rare in denervating diseases. A patient with calf enlargement associated with L5-S1 radiculopathy and another with thenar, hypothenar, forearm and calf muscle hypertrophy in the course of chronic relapsing inflammatory demyelinating polyneuropathy are described. Gastrocnemius muscle biopsy revealed both type I and type II fibre hypertrophy in the former case and predominant type I fibre hypertrophy in the latter. Passive stretching and abnormal spontaneous muscular activity might have played a role in the origin of hypertrophy in both patients, but a satisfactory explanation for denervation hypertrophy has yet to be provided.
KW - Muscle hypertrophy
KW - Neuropathies
KW - Spontaneous muscular activity
KW - Stretching
UR - http://www.scopus.com/inward/record.url?scp=0024365542&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0024365542&partnerID=8YFLogxK
U2 - 10.1007/BF00314459
DO - 10.1007/BF00314459
M3 - Article
C2 - 2760647
AN - SCOPUS:0024365542
VL - 236
SP - 292
EP - 295
JO - Journal of Neurology
JF - Journal of Neurology
SN - 0340-5354
IS - 5
ER -