Neuroimaging assessment in low level consciousness patients

Silvia Marino, Nicola De Stefano

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

Consciousness is a multifaceted concept that has two dimensions: arousal, or wakefulness (i.e., level of consciousness), and awareness (i.e., content of consciousness). An accurate and reliable assessment of the arousal and awareness of consciousness in patients with severe brain damage is of greatest importance for the differential diagnosis of low level consciousness patients and for outcome evaluation. Recent studies suggest a number of potential clinical and rehabilitative applications of magnetic resonance (MR) techniques. Although bedside clinical examination remains the criterion standard for establishing diagnosis, MR may provide an adjunctive diagnostic role when behavioural findings are very limited or ambiguous. The future of diagnostic and prognostic assessment of patients with disorders of consciousness envisions a battery of neurobehavioral and neuroimaging techniques (such as structural and functional MR imaging, MR spectroscopy, diffusion tensor imaging, fiber tracking, positron emission tomography) that serve as complementary clinical tools that may help differentiate the effects of underarousal, sensory impairment, motor dysfunction, and cognitive disturbance in the search for potential causes of behavioural unresponsiveness.

Original languageEnglish
Title of host publicationChronic Disorders of Consciousness: From Research to Clinical Practice
PublisherNova Science Publishers, Inc.
Pages61-80
Number of pages20
ISBN (Print)9781626189409
Publication statusPublished - 2013

Fingerprint

Consciousness
Neuroimaging
Magnetic Resonance Spectroscopy
Arousal
Consciousness Disorders
Diffusion Tensor Imaging
Wakefulness
Positron-Emission Tomography
Differential Diagnosis
Magnetic Resonance Imaging
Brain

ASJC Scopus subject areas

  • Medicine(all)
  • Neuroscience(all)

Cite this

Marino, S., & Stefano, N. D. (2013). Neuroimaging assessment in low level consciousness patients. In Chronic Disorders of Consciousness: From Research to Clinical Practice (pp. 61-80). Nova Science Publishers, Inc..

Neuroimaging assessment in low level consciousness patients. / Marino, Silvia; Stefano, Nicola De.

Chronic Disorders of Consciousness: From Research to Clinical Practice. Nova Science Publishers, Inc., 2013. p. 61-80.

Research output: Chapter in Book/Report/Conference proceedingChapter

Marino, S & Stefano, ND 2013, Neuroimaging assessment in low level consciousness patients. in Chronic Disorders of Consciousness: From Research to Clinical Practice. Nova Science Publishers, Inc., pp. 61-80.
Marino S, Stefano ND. Neuroimaging assessment in low level consciousness patients. In Chronic Disorders of Consciousness: From Research to Clinical Practice. Nova Science Publishers, Inc. 2013. p. 61-80
Marino, Silvia ; Stefano, Nicola De. / Neuroimaging assessment in low level consciousness patients. Chronic Disorders of Consciousness: From Research to Clinical Practice. Nova Science Publishers, Inc., 2013. pp. 61-80
@inbook{c4a1800bdaba4d9b9bded45913ce2be5,
title = "Neuroimaging assessment in low level consciousness patients",
abstract = "Consciousness is a multifaceted concept that has two dimensions: arousal, or wakefulness (i.e., level of consciousness), and awareness (i.e., content of consciousness). An accurate and reliable assessment of the arousal and awareness of consciousness in patients with severe brain damage is of greatest importance for the differential diagnosis of low level consciousness patients and for outcome evaluation. Recent studies suggest a number of potential clinical and rehabilitative applications of magnetic resonance (MR) techniques. Although bedside clinical examination remains the criterion standard for establishing diagnosis, MR may provide an adjunctive diagnostic role when behavioural findings are very limited or ambiguous. The future of diagnostic and prognostic assessment of patients with disorders of consciousness envisions a battery of neurobehavioral and neuroimaging techniques (such as structural and functional MR imaging, MR spectroscopy, diffusion tensor imaging, fiber tracking, positron emission tomography) that serve as complementary clinical tools that may help differentiate the effects of underarousal, sensory impairment, motor dysfunction, and cognitive disturbance in the search for potential causes of behavioural unresponsiveness.",
author = "Silvia Marino and Stefano, {Nicola De}",
year = "2013",
language = "English",
isbn = "9781626189409",
pages = "61--80",
booktitle = "Chronic Disorders of Consciousness: From Research to Clinical Practice",
publisher = "Nova Science Publishers, Inc.",

}

TY - CHAP

T1 - Neuroimaging assessment in low level consciousness patients

AU - Marino, Silvia

AU - Stefano, Nicola De

PY - 2013

Y1 - 2013

N2 - Consciousness is a multifaceted concept that has two dimensions: arousal, or wakefulness (i.e., level of consciousness), and awareness (i.e., content of consciousness). An accurate and reliable assessment of the arousal and awareness of consciousness in patients with severe brain damage is of greatest importance for the differential diagnosis of low level consciousness patients and for outcome evaluation. Recent studies suggest a number of potential clinical and rehabilitative applications of magnetic resonance (MR) techniques. Although bedside clinical examination remains the criterion standard for establishing diagnosis, MR may provide an adjunctive diagnostic role when behavioural findings are very limited or ambiguous. The future of diagnostic and prognostic assessment of patients with disorders of consciousness envisions a battery of neurobehavioral and neuroimaging techniques (such as structural and functional MR imaging, MR spectroscopy, diffusion tensor imaging, fiber tracking, positron emission tomography) that serve as complementary clinical tools that may help differentiate the effects of underarousal, sensory impairment, motor dysfunction, and cognitive disturbance in the search for potential causes of behavioural unresponsiveness.

AB - Consciousness is a multifaceted concept that has two dimensions: arousal, or wakefulness (i.e., level of consciousness), and awareness (i.e., content of consciousness). An accurate and reliable assessment of the arousal and awareness of consciousness in patients with severe brain damage is of greatest importance for the differential diagnosis of low level consciousness patients and for outcome evaluation. Recent studies suggest a number of potential clinical and rehabilitative applications of magnetic resonance (MR) techniques. Although bedside clinical examination remains the criterion standard for establishing diagnosis, MR may provide an adjunctive diagnostic role when behavioural findings are very limited or ambiguous. The future of diagnostic and prognostic assessment of patients with disorders of consciousness envisions a battery of neurobehavioral and neuroimaging techniques (such as structural and functional MR imaging, MR spectroscopy, diffusion tensor imaging, fiber tracking, positron emission tomography) that serve as complementary clinical tools that may help differentiate the effects of underarousal, sensory impairment, motor dysfunction, and cognitive disturbance in the search for potential causes of behavioural unresponsiveness.

UR - http://www.scopus.com/inward/record.url?scp=84892129918&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84892129918&partnerID=8YFLogxK

M3 - Chapter

AN - SCOPUS:84892129918

SN - 9781626189409

SP - 61

EP - 80

BT - Chronic Disorders of Consciousness: From Research to Clinical Practice

PB - Nova Science Publishers, Inc.

ER -