Neuroimaging in pediatric brain tumors: State of the art and perspectives

J. D. Tesoro-Tess, M. Massimino

Research output: Contribution to journalArticlepeer-review

Abstract

The continued development of neuroimaging techniques produces a constant improvement in the clinical care of patients with primary brain tumors. CT and MRI are actually considered essential imaging techniques in the radiological management of pediatric brain malignancies. On the other hand, MRI is the only imaging modality which can provide the largest amount of information for the evaluation of these tumors, both at onset and during treatment or follow-up. The routine use of paramagnetic contrast media (Gadolinium) greatly contributes to the preoperative assessment of brain tumors in children, the effectiveness of surgical and nonsurgical therapies, the onset of recurrences and iatrogenic lesions. New high-field MRI equipment allows collection of metabolic and functional data: nuclear MR spectroscopy offers a noninvasive in vivo approach to biochemical analysis, mainly useful for differential diagnosis between local recurrence and post-treatment necrosis. Furthermore, the continued development of MR technologies is providing important indications, especially in functional neuroimaging. Metabolic imaging and brain MR are providing new insights into the composition of brain tissue and changes in tissue activation.

Original languageEnglish
Pages (from-to)17-24
Number of pages8
JournalSAGGI - Child Development and Disabilities
Volume30
Issue number2
Publication statusPublished - 2004

Keywords

  • Brain tumors
  • Children
  • CT
  • Imaging
  • MRI

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Rehabilitation
  • Neuropsychology and Physiological Psychology

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