Neuroleptic induced parkinsonism: MRI findings in relation to clinical course after withdrawal of neuroleptic drugs

V. Bocola, G. Fabbrini, A. Sollecito, C. Paladini, N. Martucci

Research output: Contribution to journalArticle

Abstract

Parkinsonism is a common complication of neuroleptic drug use; however, the pathophysiology of the persistence of parkinsonian symptoms after withdrawal of neuroleptic drugs is poorly understood. Twenty patients with neuroleptic induced parkinsonism were studied by high field MRI. Persistence of symptoms was associated with different findings depending on the age of the patients - namely, putaminal hypointensity in young patients and striatal hyperintensities in old patients. High field MRI may be useful in identifying patients at higher risk for neuroleptic induced parkinsonism.

Original languageEnglish
Pages (from-to)213-216
Number of pages4
JournalJournal of Neurology, Neurosurgery and Psychiatry
Volume60
Issue number2
Publication statusPublished - Feb 1996

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Keywords

  • Magnetic resonance imaging
  • Neuroleptic drugs
  • Parkinsonism

ASJC Scopus subject areas

  • Neuropsychology and Physiological Psychology
  • Neuroscience(all)
  • Psychiatry and Mental health

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