Neurologic examination in infants with hypoxicischemic encephalopathy at age 9 to 14 months: Use of optimality scores and correlation with magnetic resonance imaging finding

Leena Haataja, Eugenio Mercuri, Andrea Guzzetta, Mary Rutherford, Serena Counsell, Maria Flavia Frisone, Giovanni Cioni, Frances Cowan, Lilly Dubowitz

Research output: Contribution to journalArticlepeer-review

Abstract

Objectives: To evaluate whether a structured and scorable neurologic examination (The Hammersmith Infant Neurological Examination) correlates with early magnetic resonance imaging findings in a group of infants with hypoxic-ischemic encephalopathy (HIE) and whether the scores of this assessment can predict the locomotor function in these children. Study design: A total of 53 term infants fulfilling the criteria for HIE underwent scanning within 4 weeks from delivery, with a 1 Tesla HPQ magnet. The scores from the neurologic examination performed between 9 to 14 months were correlated to the neonatal magnetic resonance imaging findings and to the maximal locomotor function defined at the ages of 2 and 4 years. Results: The scores were always optimal in the infants with normal or minor neonatal magnetic resonance imaging findings. The lowest scores were associated with severe basal ganglia and white matter lesions. All the infants who had a global score between 67 and 78 at 1 year were able to walk independently at 2 years and without restrictions at 4 years. Scores between 40 and 67 were associated with restricted mobility and scores

Original languageEnglish
Pages (from-to)332-337
Number of pages6
JournalJournal of Pediatrics
Volume138
Issue number3
DOIs
Publication statusPublished - 2001

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health

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