Neurological examination findings to predict limitations in mobility and falls in older persons without a history of neurological disease

Luigi Ferrucci, Stefania Bandinelli, Chiara Cavazzini, Fulvio Lauretani, Annamaria Corsi, Benedetta Bartali, Antonio Cherubini, Lenore Launer, Jack M. Guralnik

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Purpose To estimate the prevalence of neurological signs and their association with limitations in mobility and falls in a sample of older persons without known neurological disease. Methods A neurologist examined 818 participants from the InCHIANTI study who were aged ≥65 years and who did not have cognitive impairment, treatment with neuroleptics, and a history of neurological disease. Mobility was assessed as walking speed and self-reported ability to walk at least 1 km without difficulty. Participants were asked to report falls that had occurred in the previous 12 months. Results Less than 20% (160/818) of participants had no neurological signs. Neurological signs were more prevalent in older participants and those with impaired mobility. When all neurological signs were included in sex-and age-adjusted multivariate models, 10 were mutually independent correlates of poor mobility. After adjusting for age and sex, the number of neurological signs was associated with progressively slower walking speed (P

Original languageEnglish
Pages (from-to)807-815
Number of pages9
JournalAmerican Journal of Medicine
Issue number12
Publication statusPublished - Jun 15 2004


ASJC Scopus subject areas

  • Nursing(all)

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