TY - JOUR
T1 - Neuromodulation in treatment of refractory headaches
AU - Franzini, Angelo
AU - Leone, Massimo
AU - Messina, Giuseppe
AU - Cordella, Roberto
AU - Marras, Carlo
AU - Bussone, Gennaro
AU - Broggi, Giovanni
PY - 2008/5
Y1 - 2008/5
N2 - The field of neuromodulation is emerging as a promising and alternative therapeutical option for many drug-resistant clinical conditions, including painful syndromes such as refractory chronic cluster headache (CCH) and trigeminal neuralgia. We here report a series of patients who have undergone Deep Brain Stimulation (DBS) of Posterior Hypothalamus for chronic cluster headache, trigeminal neuralgia and atypical facial pain, matching their corresponding clinical results and also suggesting a role for Great Occipital Nerve Stimulation (which is a much less invasive procedure) in the treatment of CCH. According to us, the refinement of surgical techniques and of metabolic and functional brain neuroradiological investigations will lead to a refinement of the therapeutical strategies in such patients.
AB - The field of neuromodulation is emerging as a promising and alternative therapeutical option for many drug-resistant clinical conditions, including painful syndromes such as refractory chronic cluster headache (CCH) and trigeminal neuralgia. We here report a series of patients who have undergone Deep Brain Stimulation (DBS) of Posterior Hypothalamus for chronic cluster headache, trigeminal neuralgia and atypical facial pain, matching their corresponding clinical results and also suggesting a role for Great Occipital Nerve Stimulation (which is a much less invasive procedure) in the treatment of CCH. According to us, the refinement of surgical techniques and of metabolic and functional brain neuroradiological investigations will lead to a refinement of the therapeutical strategies in such patients.
KW - Cluster headache
KW - Neuromodulation
KW - Trigeminal neuralgia
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U2 - 10.1007/s10072-008-0891-8
DO - 10.1007/s10072-008-0891-8
M3 - Article
C2 - 18545901
AN - SCOPUS:45249100433
VL - 29
JO - Neurological Sciences
JF - Neurological Sciences
SN - 1590-1874
IS - SUPPL. 1
ER -