Neuromyelitis optica in a child with atypical onset and severe outcome

Nicoletta Milani, F. Zibordi, A. Erbetta, B. Pollo, L. Angelin

Research output: Contribution to journalArticlepeer-review


We report on a seven-year-old boy with inflammatory relapsing-remitting CNS disease, involving the optic nerves and spinal cord, with increasingly severe sequelae after each relapse. Clinical course, neuroimaging and laboratory findings were consistent with neuromyelitis optica. Biopsy of leptomeninges and underlying nervous tissue showed increased vascularization and thickened hyalinized vessel walls, reported as suggestive for neuromyelitis optica. Clinical features at onset were atypical, rendering the case highly unusual and the diagnosis tentative.

Original languageEnglish
Pages (from-to)198-201
Number of pages4
Issue number3
Publication statusPublished - Jun 2004


  • Children
  • Neuromyelitis optica

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Clinical Neurology


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