Neuropathology

Silvia Romano; Carlo Caltagirone; Ugo Nocentini

doi:10.1007/978-88-470-2676-6_5

Neuropathology

Silvia Romano, Carlo Caltagirone, Ugo Nocentini

Fondazione Santa Lucia

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Abstract

The typical histopathological lesion of MS is the demyelinating plaque from which the alternative name sclerose en plaques derives. It is well established that plaques are present not only in the white matter of the brain, cerebellum, brainstem and spinal cord, but also in the gray matter. The introduction of double inversion recovery MRI sequences has made possible to show that cortical lesions are consistently present, not only in patients with a progressive disease but also in patients with CIS and RR MS. Several classifications of the plaques based on the activity level of pathological processes, disease stage and supposed pathogenetic processes have been proposed.

Original language	English
Title of host publication	Neuropsychiatric Dysfunction in Multiple Sclerosis
Publisher	Springer-Verlag Italia s.r.l.
Pages	27-29
Number of pages	3
Volume	9788847026766
ISBN (Print)	9788847026766, 884702675X, 9788847026759
DOIs	https://doi.org/10.1007/978-88-470-2676-6_5
Publication status	Published - May 1 2012

ASJC Scopus subject areas

Medicine(all)

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10.1007/978-88-470-2676-6_5

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