Neurophysiological classification and sensitivity in 500 carpal tunnel syndrome hands

L. Padua, M. LoMonaco, B. Gregori, E. M. Valente, R. Padua, P. Tonali

Research output: Contribution to journalArticlepeer-review


Objectives - To evaluate the following points about carpal tunnel syndrome (CTS): 1) characterization of a wide population; 2) sensitivity of electrodiagnostic tests, and particularly the contribution of disto-proximal ratio test; 3) validity of a neurophysiological classification developed by us. Material and methods - Prospective study in 500 hands with CTS symptoms. Neurophysiological 'standard' tests were always performed: sensory nerve conduction velocity (SNCV) first- and third digit-wrist and distal motor latency (DML). In 'standard negative' hands disto-proximal ratio technique (R) was performed. Neurophysiological classification: Extreme CTS (absence of median motor, sensory responses), Severe (absence of sensory response, abnormal DML), Moderate (abnormal SNCV, abnormal DML), Mild (abnormal SNCV, normal DML), Minimal (abnormal R or other segmental/comparative test, normal standard tests). Results Sensibility of standard tests: 77%. R increased the diagnostic yield by 20%. CTS classification appeared reliable with significant differences between groups. Conclusion - R is a useful test, the classification may be useful in clinical/therapeutical decisions.

Original languageEnglish
Pages (from-to)211-217
Number of pages7
JournalActa Neurologica Scandinavica
Issue number4
Publication statusPublished - 1997


  • Carpal tunnel syndrome
  • Classification
  • Disto-proximal ratio
  • Neurophysiology

ASJC Scopus subject areas

  • Clinical Neurology
  • Neuroscience(all)


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