Neurophysiological evaluation of sexual dysfunction in patients operated for colorectal cancer

Alberto Pietrangeli, Loredana Bove, Pierluigi Innocenti, Andrea Pace, Carlo Tirelli, Eugenio Santoro, Bruno Jandolo

Research output: Contribution to journalArticlepeer-review


Sexual dysfunction after colorectal cancer surgery may be severe and occurs in 25% to 100% of cases. Thirty-eight patients underwent colorectal resection; eight (21%) who were totally impotent and two (5%) who had ejaculatory failure were therefore studied to better understand the neurophysiological alterations related to this type of surgery. The patients were evaluated after surgery with electrophysiological testing, including examination of the sacral reflex (SR), pudendal somatosensory evoked potential (PEP), and motor evoked potential (MEP) responses. Sudomotor skin response (SSR) was also studied in a group of patients. Of the 38 patients studied, 29 showed abnormalities: six of SR, three of PEP, six of MEP, and fourteen of SSR. Only a combination of all these tests permits correct evaluation of the sexual dysfunction.

Original languageEnglish
Pages (from-to)353-357
Number of pages5
JournalClinical Autonomic Research
Issue number6
Publication statusPublished - 1998


  • Colorectal cancer
  • Impotence
  • Pudendal evoked potential

ASJC Scopus subject areas

  • Clinical Neurology
  • Neuroscience(all)


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