Neurophysiological examination of end-plate function in patients with lung cancer

B. Jandolo, M. D. Giulia, A. Pace, A. Pietrangeli, L. Bove, P. Innocenti, M. Lopez

Research output: Contribution to journalArticle

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Abstract

Twenty-eight patients affected by lung cancer were studied with neurophysiological and clinical examinations to show the prevalence of alteration of neuromuscular transmission. During repetitive stimulation at 20 Hz we found in 6 cases (22%) an increment (> 20%) and in 4 cases a decrement (> 10%) of the size of muscle action potentials. In 15 patients (57%) we found low sensory action potential amplitude (<11 μv). In 3 (11%) of the 6 cases with incremental response the overall examination suggested a disorder of neuromuscular junction such as Eaton-Lambert syndrome. Our results suggest that the peripheral nervous system involvement in patients affected by lung cancer is higher than usually estimated.

Original languageEnglish
Pages (from-to)247-250
Number of pages4
JournalElectromyography and Clinical Neurophysiology
Volume35
Issue number4
Publication statusPublished - 1995

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Lung Neoplasms
Action Potentials
Neuromuscular Junction Diseases
Lambert-Eaton Myasthenic Syndrome
Peripheral Nervous System
Muscles

ASJC Scopus subject areas

  • Physiology
  • Clinical Neurology

Cite this

Jandolo, B., Giulia, M. D., Pace, A., Pietrangeli, A., Bove, L., Innocenti, P., & Lopez, M. (1995). Neurophysiological examination of end-plate function in patients with lung cancer. Electromyography and Clinical Neurophysiology, 35(4), 247-250.

Neurophysiological examination of end-plate function in patients with lung cancer. / Jandolo, B.; Giulia, M. D.; Pace, A.; Pietrangeli, A.; Bove, L.; Innocenti, P.; Lopez, M.

In: Electromyography and Clinical Neurophysiology, Vol. 35, No. 4, 1995, p. 247-250.

Research output: Contribution to journalArticle

Jandolo, B, Giulia, MD, Pace, A, Pietrangeli, A, Bove, L, Innocenti, P & Lopez, M 1995, 'Neurophysiological examination of end-plate function in patients with lung cancer', Electromyography and Clinical Neurophysiology, vol. 35, no. 4, pp. 247-250.
Jandolo, B. ; Giulia, M. D. ; Pace, A. ; Pietrangeli, A. ; Bove, L. ; Innocenti, P. ; Lopez, M. / Neurophysiological examination of end-plate function in patients with lung cancer. In: Electromyography and Clinical Neurophysiology. 1995 ; Vol. 35, No. 4. pp. 247-250.
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