Abstract
Myoclonus is the most common motor clinical manifestation of photosensitivity. We investigated, by means of computerized video-polygraphic techniques, the neurophysiological characteristics of photic-induced myoclonia in four patients with progressive myoclonus epilepsies and marked photosensitivity. In all four patients, intermittent photic stimulation induced either focal or massive myoclonic jerks. Myoclonic jerks at the limbs were associated with a contralateral cortical potential, whose peak preceded the onset of the myoclonic potential by a latency compatible with a conduction along direct cortico-spinal pathways. Propagation of photic- induced myoclonia in different cranial and limb muscles followed a rostro- caudal pattern. Our findings indicate a cortical origin of photic-induced myoclonia in PME, with neurophysiological features similar to those described in photic cortical reflex myoclonus.
| Original language | Italian |
|---|---|
| Pages (from-to) | 351-353 |
| Number of pages | 3 |
| Journal | Bollettino - Lega Italiana contro l'Epilessia |
| Issue number | 99 |
| Publication status | Published - 1997 |
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ASJC Scopus subject areas
- Clinical Neurology
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Meccanismi neurofisiologici delle manifestazioni motorie nelle epilessie fotosensibili. / Rubboli, G.; Meletti, S.; Strafella, A.; Zaniboni, A.; Pastorelli, F.; Valzania, F.; Tassinari, C. A.
In: Bollettino - Lega Italiana contro l'Epilessia, No. 99, 1997, p. 351-353.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Meccanismi neurofisiologici delle manifestazioni motorie nelle epilessie fotosensibili
AU - Rubboli, G.
AU - Meletti, S.
AU - Strafella, A.
AU - Zaniboni, A.
AU - Pastorelli, F.
AU - Valzania, F.
AU - Tassinari, C. A.
PY - 1997
Y1 - 1997
N2 - Myoclonus is the most common motor clinical manifestation of photosensitivity. We investigated, by means of computerized video-polygraphic techniques, the neurophysiological characteristics of photic-induced myoclonia in four patients with progressive myoclonus epilepsies and marked photosensitivity. In all four patients, intermittent photic stimulation induced either focal or massive myoclonic jerks. Myoclonic jerks at the limbs were associated with a contralateral cortical potential, whose peak preceded the onset of the myoclonic potential by a latency compatible with a conduction along direct cortico-spinal pathways. Propagation of photic- induced myoclonia in different cranial and limb muscles followed a rostro- caudal pattern. Our findings indicate a cortical origin of photic-induced myoclonia in PME, with neurophysiological features similar to those described in photic cortical reflex myoclonus.
AB - Myoclonus is the most common motor clinical manifestation of photosensitivity. We investigated, by means of computerized video-polygraphic techniques, the neurophysiological characteristics of photic-induced myoclonia in four patients with progressive myoclonus epilepsies and marked photosensitivity. In all four patients, intermittent photic stimulation induced either focal or massive myoclonic jerks. Myoclonic jerks at the limbs were associated with a contralateral cortical potential, whose peak preceded the onset of the myoclonic potential by a latency compatible with a conduction along direct cortico-spinal pathways. Propagation of photic- induced myoclonia in different cranial and limb muscles followed a rostro- caudal pattern. Our findings indicate a cortical origin of photic-induced myoclonia in PME, with neurophysiological features similar to those described in photic cortical reflex myoclonus.
KW - Myoclonus
KW - Photic Cortical Reflex Myoclonus
KW - Photosensitivity
KW - Progressive Myoclonus Epilepsies
UR - http://www.scopus.com/inward/record.url?scp=0031420893&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0031420893&partnerID=8YFLogxK
M3 - Articolo
AN - SCOPUS:0031420893
SP - 351
EP - 353
JO - Bollettino - Lega Italiana contro l'Epilessia
JF - Bollettino - Lega Italiana contro l'Epilessia
SN - 0394-560X
IS - 99
ER -