TY - JOUR
T1 - Neuroplastic changes in the brain
T2 - A case of two successive adaptive changes within the motor cortex
AU - Raz, Eytan
AU - Tinelli, Emanuele
AU - Guidetti, Giulio
AU - Totaro, Porzia
AU - Bozzao, Luigi
AU - Pantano, Patrizia
PY - 2010
Y1 - 2010
N2 - Abstract We describe a case of neuroplasticity associated with both arteriovenous malformation (AVM) and stroke, which occurred in two successive events in the same patient. Functional magnetic resonance imaging (fMRI) during right-hand movement in a young man with a left rolandic AVM detected activation of a region corresponding to the left premotor cortex. The AVM was embolized. A few hours after the last embolization session, the patient sustained an ischemic complication in the left subcortical white matter. A second fMRI detected a lower degree of left premotor cortex activation and strong activation of the contralesional right primary motor cortex and bilateral supplementary motor areas. One month later, in association with clinical recovery, the fMRI activation returned to that observed in the first fMRI, ie, selective activation of the ipsilesional left premotor cortex. This is, to our knowledge, the first description of two distinct functional cortical changes determined by an AVM and a stroke within the motor network.
AB - Abstract We describe a case of neuroplasticity associated with both arteriovenous malformation (AVM) and stroke, which occurred in two successive events in the same patient. Functional magnetic resonance imaging (fMRI) during right-hand movement in a young man with a left rolandic AVM detected activation of a region corresponding to the left premotor cortex. The AVM was embolized. A few hours after the last embolization session, the patient sustained an ischemic complication in the left subcortical white matter. A second fMRI detected a lower degree of left premotor cortex activation and strong activation of the contralesional right primary motor cortex and bilateral supplementary motor areas. One month later, in association with clinical recovery, the fMRI activation returned to that observed in the first fMRI, ie, selective activation of the ipsilesional left premotor cortex. This is, to our knowledge, the first description of two distinct functional cortical changes determined by an AVM and a stroke within the motor network.
KW - arterovenous malformation
KW - fMRI
KW - neuroplasticity
KW - stroke
UR - http://www.scopus.com/inward/record.url?scp=77954641050&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=77954641050&partnerID=8YFLogxK
U2 - 10.1111/j.1552-6569.2008.00346.x
DO - 10.1111/j.1552-6569.2008.00346.x
M3 - Article
C2 - 19187472
AN - SCOPUS:77954641050
VL - 20
SP - 297
EP - 301
JO - Journal of Neuroimaging
JF - Journal of Neuroimaging
SN - 1051-2284
IS - 3
ER -