Abstract
The neuropsychological performances, outcome of epilepsy and MRI topography of tubers of 23 children with tuberous sclerosis were reviewed. Seven children had normal intelligence, 10 had mental retardation, and six mental retardation and autism. An adverse association was found between the number of lesions and IQ, behaviour and severity of epilepsy. Posterior lesions, in addition to frontal-lobe dysfunction, were observed in children with autism. Tuberous sclerosis with well-defined cerebral lesions may represent a model for the relationship between different neuropsychiatric problems.
| Original language | English |
|---|---|
| Pages (from-to) | 698-705 |
| Number of pages | 8 |
| Journal | Developmental Medicine and Child Neurology |
| Volume | 33 |
| Issue number | 8 |
| Publication status | Published - 1991 |
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ASJC Scopus subject areas
- Clinical Neurology
- Pediatrics, Perinatology, and Child Health
- Neuroscience(all)
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Neuropsychological aspects of tuberous sclerosis in relation to epilepsy and MRI findings. / Jambaque, I.; Cusmai, R.; Curatolo, P.; Cortesi, F.; Perrot, C.; Dulac, O.
In: Developmental Medicine and Child Neurology, Vol. 33, No. 8, 1991, p. 698-705.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Neuropsychological aspects of tuberous sclerosis in relation to epilepsy and MRI findings
AU - Jambaque, I.
AU - Cusmai, R.
AU - Curatolo, P.
AU - Cortesi, F.
AU - Perrot, C.
AU - Dulac, O.
PY - 1991
Y1 - 1991
N2 - The neuropsychological performances, outcome of epilepsy and MRI topography of tubers of 23 children with tuberous sclerosis were reviewed. Seven children had normal intelligence, 10 had mental retardation, and six mental retardation and autism. An adverse association was found between the number of lesions and IQ, behaviour and severity of epilepsy. Posterior lesions, in addition to frontal-lobe dysfunction, were observed in children with autism. Tuberous sclerosis with well-defined cerebral lesions may represent a model for the relationship between different neuropsychiatric problems.
AB - The neuropsychological performances, outcome of epilepsy and MRI topography of tubers of 23 children with tuberous sclerosis were reviewed. Seven children had normal intelligence, 10 had mental retardation, and six mental retardation and autism. An adverse association was found between the number of lesions and IQ, behaviour and severity of epilepsy. Posterior lesions, in addition to frontal-lobe dysfunction, were observed in children with autism. Tuberous sclerosis with well-defined cerebral lesions may represent a model for the relationship between different neuropsychiatric problems.
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UR - http://www.scopus.com/inward/citedby.url?scp=0025786901&partnerID=8YFLogxK
M3 - Article
C2 - 1916024
AN - SCOPUS:0025786901
VL - 33
SP - 698
EP - 705
JO - Developmental Medicine and Child Neurology
JF - Developmental Medicine and Child Neurology
SN - 0012-1622
IS - 8
ER -