Neuropsychological aspects of tuberous sclerosis in relation to epilepsy and MRI findings

I. Jambaque, R. Cusmai, P. Curatolo, F. Cortesi, C. Perrot, O. Dulac

Research output: Contribution to journalArticle

127 Citations (Scopus)

Abstract

The neuropsychological performances, outcome of epilepsy and MRI topography of tubers of 23 children with tuberous sclerosis were reviewed. Seven children had normal intelligence, 10 had mental retardation, and six mental retardation and autism. An adverse association was found between the number of lesions and IQ, behaviour and severity of epilepsy. Posterior lesions, in addition to frontal-lobe dysfunction, were observed in children with autism. Tuberous sclerosis with well-defined cerebral lesions may represent a model for the relationship between different neuropsychiatric problems.

Original languageEnglish
Pages (from-to)698-705
Number of pages8
JournalDevelopmental Medicine and Child Neurology
Volume33
Issue number8
Publication statusPublished - 1991

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Tuberous Sclerosis
Epilepsy
Autistic Disorder
Intellectual Disability
Frontal Lobe
Intelligence

ASJC Scopus subject areas

  • Clinical Neurology
  • Pediatrics, Perinatology, and Child Health
  • Neuroscience(all)

Cite this

Neuropsychological aspects of tuberous sclerosis in relation to epilepsy and MRI findings. / Jambaque, I.; Cusmai, R.; Curatolo, P.; Cortesi, F.; Perrot, C.; Dulac, O.

In: Developmental Medicine and Child Neurology, Vol. 33, No. 8, 1991, p. 698-705.

Research output: Contribution to journalArticle

Jambaque, I, Cusmai, R, Curatolo, P, Cortesi, F, Perrot, C & Dulac, O 1991, 'Neuropsychological aspects of tuberous sclerosis in relation to epilepsy and MRI findings', Developmental Medicine and Child Neurology, vol. 33, no. 8, pp. 698-705.
Jambaque, I. ; Cusmai, R. ; Curatolo, P. ; Cortesi, F. ; Perrot, C. ; Dulac, O. / Neuropsychological aspects of tuberous sclerosis in relation to epilepsy and MRI findings. In: Developmental Medicine and Child Neurology. 1991 ; Vol. 33, No. 8. pp. 698-705.
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