Neuropsychological assessment in patients with relapsing-remitting multiple sclerosis and mild functional impairment: correlation with magnetic resonance imaging

G. P. Anzola, L. Bevilacqua, S. F. Cappa, R. Capra, L. Faglia, E. Farina, G. Frisoni, C. Mariani, M. P. Pasolini, L. A. Vignolo

Research output: Contribution to journalArticle

Abstract

Forty one moderately impaired patients with clinically confirmed multiple sclerosis (MS) and a relapsing-remitting course were submitted to a neuropsychological battery and magnetic resonance imaging (MRI) to correlate the neuropsychological performances with the degree of cerebral demyelination. The neuropsychological results were indicative of a very mild overall impairment. The patients were subdivided into two groups (extensive periventricular demyelination or discrete lesions on MRI) and the results of neuropsychological tests compared. Patients with extensive periventricular demyelination had an inferior performance on concept formation, non-verbal reasoning and verbal memory tests.

Original languageEnglish
Pages (from-to)142-145
Number of pages4
JournalJournal of Neurology, Neurosurgery and Psychiatry
Volume53
Issue number2
Publication statusPublished - 1990

ASJC Scopus subject areas

  • Psychiatry and Mental health
  • Neuroscience(all)
  • Neuropsychology and Physiological Psychology

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