Neuropsychological Deterioration Predicts Tumor Progression in a Young Boy With Bithalamic Glioma

Laura Peruzzi, Laura Iuvone, Antonio Ruggiero, Cesare Colosimo, Maria Chiara Stefanini, Riccardo Riccardi

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

A description is given of the clinical, neuropsychological, and neuroimaging evolution of a 12-year-old boy (CG) who presented with bilateral thalamic astrocytoma (World Health Organization Grade 2). CG underwent an extensive neuropsychological assessment immediately after biopsy prior to any medical therapies and was followed up for 3 years until death. Neuropsychological functioning was thoroughly investigated by means of a detailed battery that included intelligence and cognitive functions. Evolution was characterized by cognitive deterioration that preceded neuroimaging signs of tumor progression. Starting from normal cognitive organization, the child exhibited visuospatial memory deficits and, afterward, diffuse cognitive impairment. The role of neuropsychological assessment in detecting early disease progression is discussed, mainly for rare pathologies whose evolution may be extremely variable.

Original languageEnglish
Pages (from-to)76-81
Number of pages6
JournalApplied Neuropsychology: Child
Volume5
Issue number1
DOIs
Publication statusPublished - Jan 2 2016

Fingerprint

Neuroimaging
Glioma
Astrocytoma
Memory Disorders
Intelligence
Cognition
Disease Progression
Neoplasms
Pathology
Biopsy
Therapeutics
Cognitive Dysfunction

Keywords

  • bithalamic tumor
  • children
  • cognitive deterioration
  • neuropsychological assessment
  • progressive neurological diseases
  • visual spatial memory

ASJC Scopus subject areas

  • Developmental and Educational Psychology
  • Neuropsychology and Physiological Psychology

Cite this

Neuropsychological Deterioration Predicts Tumor Progression in a Young Boy With Bithalamic Glioma. / Peruzzi, Laura; Iuvone, Laura; Ruggiero, Antonio; Colosimo, Cesare; Stefanini, Maria Chiara; Riccardi, Riccardo.

In: Applied Neuropsychology: Child, Vol. 5, No. 1, 02.01.2016, p. 76-81.

Research output: Contribution to journalArticle

Peruzzi, L, Iuvone, L, Ruggiero, A, Colosimo, C, Stefanini, MC & Riccardi, R 2016, 'Neuropsychological Deterioration Predicts Tumor Progression in a Young Boy With Bithalamic Glioma', Applied Neuropsychology: Child, vol. 5, no. 1, pp. 76-81. https://doi.org/10.1080/21622965.2014.960566
Peruzzi, Laura ; Iuvone, Laura ; Ruggiero, Antonio ; Colosimo, Cesare ; Stefanini, Maria Chiara ; Riccardi, Riccardo. / Neuropsychological Deterioration Predicts Tumor Progression in a Young Boy With Bithalamic Glioma. In: Applied Neuropsychology: Child. 2016 ; Vol. 5, No. 1. pp. 76-81.
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