Neuropsychological functioning in children and adolescents with restrictive-type anorexia nervosa: An in-depth investigation with NEPSY-II

Sara Calderoni, Filippo Muratori, Chiara Leggero, Antonio Narzisi, Fabio Apicella, Umberto Balottin, Tiziana Carigi, Sandra Maestro, Franco Fabbro, Cosimo Urgesi

Research output: Contribution to journalArticlepeer-review

Abstract

Several studies have investigated the neuropsychological functioning of patients with anorexia nervosa restrictive type (AN-r), but results are conflicting. Here we compared the neuropsychological profile of 23 female children and adolescents with AN-r and of 46 typical controls (aged 9-16 years) using the second edition of the NEPSY (a Developmental Neuropsychology Assessment) neuropsychological battery. AN-r patients presented subtle cognitive flexibility impairments in audiomotor responses (p =.033). Conversely, superior performance in verbal fluency (p =.024) and memory (p =.034) was observed only in AN-r patients with an associated unipolar mood disorder. This profile of marginally impaired and enhanced performance was independent from illness duration and starvation degree, suggesting that it may preexist and represent a vulnerability factor for the disease onset.

Original languageEnglish
Pages (from-to)167-179
Number of pages13
JournalJournal of Clinical and Experimental Neuropsychology
Volume35
Issue number2
DOIs
Publication statusPublished - Feb 1 2013

Keywords

  • Adolescents
  • Anorexia nervosa
  • Eating disorders
  • Executive functions
  • Verbal fluency

ASJC Scopus subject areas

  • Clinical Neurology
  • Neurology
  • Clinical Psychology

Fingerprint

Dive into the research topics of 'Neuropsychological functioning in children and adolescents with restrictive-type anorexia nervosa: An in-depth investigation with NEPSY-II'. Together they form a unique fingerprint.

Cite this