Neuropsychological impairment in early-onset hydrocephalus and epilepsy with continuous spike-waves during slow-wave sleep: A case report and literature review

Annio Posar, Antonia Parmeggiani

Research output: Contribution to journalArticle

Abstract

Epilepsy with continuous spike-waves during slow-wave sleep (CSWS) is often characterized by a severe cognitive and behavioral impairment. Symptomatic cases also include patients with an early-onset hydrocephalus, but in literature detailed neuropsychological data on these subjects are not available. We describe the results of serial cognitive assessments in a girl with shunted early-onset hydrocephalus, followed by partial epilepsy complicated with CSWS at 4 years 10 months, in which a dramatic cognitive and behavioral deterioration occurred few months after CSWS onset. Adrenocorticotropic hormone treatment improved both clinical and electroencephalogram picture, but an impairment of visual perception, visual-motor coordination and executive functions persisted after CSWS disappearance. We hypothesize, in this case, an involvement of right occipital-parietal lobe and prefrontal lobe.

Original languageEnglish
Pages (from-to)141-145
Number of pages5
JournalJournal of Pediatric Neurosciences
Volume8
Issue number2
DOIs
Publication statusPublished - May 2013

Keywords

  • Choroid plexus papilloma
  • continuous spike-waves during slow-wave sleep
  • epilepsy
  • hydrocephalus
  • neuropsychological impairment

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Neuroscience(all)

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