Neuropsychological outcome of operated cerebral aneurysms: Prognostic factors on 148 patients

A. De Santis, M. Laiacona, R. Barbarotto, O. De Divitiis, M. Migliore, E. Capitani

Research output: Contribution to journalArticle

Abstract

Objectives - To analyse prognostic factors in patients operated upon for cerebral aneurysms. A previous investigation by our group showed that patients operated later than 10 days after bleeding have a worse neuropsychological prognosis, but the number of patients operated upon within 3 days was not sufficient. Here, a new sample of patients with early surgery is included in the analyses. Material and methods - Patients numbered 148 (65 with ACoA, 39 with MCA, and 44 with PCoA aneurysms): 56 were operated within 3 days, 44 within 4-10 days, and 48 after at least 10 days from bleeding. A standardized battery of 13 neuropsychological tests was adopted: we considered both the number of defective scores and the average performance. Results - Patients operated later than 10 days after bleeding had a worse prognosis than the 2 groups with early and intermediate surgery, which were not different. Aneurysm site was not relevant. Old age and low education were associated with a worse prognosis. Hunt and Hess scores at operation and post operation were also predictive of the outcome. Conclusion - On the whole, patients operated upon later than 10 days after bleeding have a less favourable prognosis than those with earlier operation timing.

Original languageEnglish
Pages (from-to)393-397
Number of pages5
JournalActa Neurologica Scandinavica
Volume97
Issue number6
Publication statusPublished - 1998

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Keywords

  • Intracranial aneurysms
  • Neuropsychological outcome
  • Prognostic factors
  • Timing of surgery

ASJC Scopus subject areas

  • Clinical Neurology
  • Neuroscience(all)

Cite this

De Santis, A., Laiacona, M., Barbarotto, R., De Divitiis, O., Migliore, M., & Capitani, E. (1998). Neuropsychological outcome of operated cerebral aneurysms: Prognostic factors on 148 patients. Acta Neurologica Scandinavica, 97(6), 393-397.