Translated title of the contribution: Neuroradiological and neuropathological correlations

M. Bozzi, C. Baldoli, M. R. Terreni, A. Rocca, P. Mortini, E. Rovere, G. L. Taccagni, G. Scotti

Research output: Contribution to journalArticlepeer-review


A 62 year old woman, complaining for some years of vague numbness and weakness of both legs getting worse in the last few months. Neurologic examination reveals only mild weakness of the right leg and bilateral painful disesthesias of both legs. Plain films of the lumbar spine demonstrate scalloping of the posterior margin of L4 with complete erosion of both pedicles of the same vertebra. CR and MR reveal a large space occupying lesion growing within the canal, apparently replacing or infiltrating the thecal sac, and producing marked widening of the canal, erosion of the posterior part of the vertebral body of L4, erosion-destruction of both pedicles and destruction of the lamina and facets on the right side. Differential diagnosis is not easy, since it is first of all difficult to precisely locate the lesion with respect to the thecal sac; it is in fact difficult to say whether the lesion is intra or extradural. Also the relationship with the bony structures is not clear: there is both evidence of remodeling (erosion) and infiltration and replacement (destruction). For these reasons the most common intradural lesions (ependymoma, neurinoma and meningioma) seem unlikely. A dermoid or epidermoid seems unlikely because of the signal on MR; primary bone tumors are unlikely, due to the secondary involvemnt of bone. A chordoma or a very rare paraganglioma have been taken into consideration.

Translated title of the contributionNeuroradiological and neuropathological correlations
Original languageItalian
Pages (from-to)401-414
Number of pages14
JournalRivista di Neuroradiologia
Issue number3
Publication statusPublished - 1995

ASJC Scopus subject areas

  • Clinical Neurology
  • Radiology Nuclear Medicine and imaging
  • Radiological and Ultrasound Technology


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