In the past two decades the clinical and microbiological spectrum of infectious endocarditis (IE) significantly changed, as well as diagnostic and therapeutic methods. The most important difference with the past years is related to the increasing number of both patients with prosthetic valves implants and drug abusers. Optimal management is based on the synergistic combinations of two or more antibiotics. Outpatient parenteral antimicrobial therapy (OPAT) is a new and an interesting option. It has been demonstrated to be safe and cost/effective for medically stable patients with viridans streptococcal endocarditis.
|Translated title of the contribution||New advances in antibiotic therapy of infective endocarditis|
|Number of pages||13|
|Journal||Trends in Medicine|
|Publication status||Published - Jan 2005|
ASJC Scopus subject areas
- Internal Medicine
- Pharmacology (medical)