Translated title of the contribution: New antiepileptic drugs

V. Loreto, A. Mariniello, S. Striano

Research output: Contribution to journalArticlepeer-review


Over 20% of epileptic patients are resistant to treatment with the currently available antiepileptic drugs (AEDs). Only for a subset of such drug-resistant (DR) patients brain surgery is suitable. Several new compounds have been recently introduced in therapy, decreasing significantly the number of DR patients. Other putative AEDs are in advanced stage of clinical evaluation. The present review briefly deals with data available in the literature on felbamate, gabapentin, lamotrigine and vigabatrin. Furthermore, the authors report their own data regarding the use of vigabatrin either as 'add-on therapy' in patients with DR partial epilepsy, either as monotherapy in newly diagnosed patients with symptomatic or cryptogenic partial epilepsy.

Translated title of the contributionNew antiepileptic drugs
Original languageItalian
Pages (from-to)945-966
Number of pages22
JournalNeurologia Psichiatria Scienze Umane
Issue number6
Publication statusPublished - 1994

ASJC Scopus subject areas

  • Neuropsychology and Physiological Psychology


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