New antigen for antibody detection in myasthenia gravis

C. Gotti, R. Mantegazza, F. Clementi

Research output: Contribution to journalArticle

22 Citations (Scopus)

Abstract

We assayed anti-acetylcholine receptor (AChR) antibodies in 61 myasthenic patients using human and fetal calf muscle AChR as antigen. Anti-AChR antibodies were detected in 85% of patients with human AChR and in 80% with fetal calf AChR. In 27 patients, the titers detected with fetal calf AChR were higher than those obtained with human AChR. Titers with different fetal calf AChR preparations were reproducible. Fetal calf AChR is a suitable antigen for immunologic analysis of myasthenic patients.

Original languageEnglish
Pages (from-to)374-377
Number of pages4
JournalNeurology
Volume34
Issue number3
Publication statusPublished - 1984

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Myasthenia Gravis
Cholinergic Receptors
Antigens
Antibodies
Muscle Weakness
Muscles

ASJC Scopus subject areas

  • Arts and Humanities (miscellaneous)
  • Clinical Neurology
  • Neuroscience(all)

Cite this

Gotti, C., Mantegazza, R., & Clementi, F. (1984). New antigen for antibody detection in myasthenia gravis. Neurology, 34(3), 374-377.

New antigen for antibody detection in myasthenia gravis. / Gotti, C.; Mantegazza, R.; Clementi, F.

In: Neurology, Vol. 34, No. 3, 1984, p. 374-377.

Research output: Contribution to journalArticle

Gotti, C, Mantegazza, R & Clementi, F 1984, 'New antigen for antibody detection in myasthenia gravis', Neurology, vol. 34, no. 3, pp. 374-377.
Gotti, C. ; Mantegazza, R. ; Clementi, F. / New antigen for antibody detection in myasthenia gravis. In: Neurology. 1984 ; Vol. 34, No. 3. pp. 374-377.
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