New antiplatelet strategies

Research output: Contribution to journalArticlepeer-review

Abstract

In the 1960s, the platelet inhibitory properties of several drugs were discovered. Like aspirin, they were already in clinical use for other therapeutic indications. Since then, the search for new and more rational antiplatelet strategies has been constant but only moderately successful, although new molecules with high selectivity for platelet function have been developed. The authors briefly review some recent advances in platelet pharmacology and focus their attention on pharmacogenetics, a potential approach to new antiplatelet strategies. Would this approach be successful, individuals rather than epidemiologically defined groups of patients might better benefit from newly targeted antiplatelet drugs.

Original languageEnglish
Pages (from-to)7-9
Number of pages3
JournalItalian Heart Journal Supplement
Volume2
Issue number1
Publication statusPublished - 2001

Keywords

  • Antiplatelet drugs
  • Aspirin
  • Dietary habits
  • Pharmacogenetics
  • Platelet glycoproteins
  • Platelets

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

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